STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rrp45Rrp45, isoform A; AU-rich element binding. (412 aa)    
Predicted Functional Partners:
Rrp4
Rrp4, isoform A; Rrp4 (Rrp4) encodes a protein involved in gene expression regulation.
   
 0.999
Mtr3
FI01414p.
   
 0.999
Csl4
RE36848p; RNA binding. It is involved in the biological process described with: RNA processing; regulation of gene expression.
   
 0.999
Ski6
Ski6, isoform A; Ski6 (Ski6) encodes a protein involved in gene expression regulation.
   
 0.999
Rrp46
FI06805p; Rrp46 (Rrp46) encodes a protein involved in gene expression regulation.
   
 0.999
Dis3
Dis3, isoform A; Dis3 (Dis3) encodes an exoribonuclease that forms part of the RNA processing exosome complex. It is involved in the regulation of cell cycle progresion, microRNA expression and mRNA surveillance; Belongs to the RNR ribonuclease family.
   
 0.999
Rrp42
IP10364p; AU-rich element binding.
  
0.999
Rrp47
Ribosomal RNA processing 47, isoform A; RNA binding; DNA binding. It is involved in the biological process described with: maturation of 5.8S rRNA; regulation of gene expression.
   
 0.999
Rrp6
Rrp6, isoform B; Rrp6 (Rrp6) encodes an exoribonuclease that forms part of the RNA processing exosome complex. It is involved in the regulation of cell cycle progresion and mRNA surveillance.
   
 0.999
Mtr4
Mtr4 helicase (Mtr4) encodes an RNA helicase involved in the viral defense response.
   
 0.998
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.