node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG10472 | CG4653 | FBpp0076774 | FBpp0074095 | RE65433p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | 0.868 |
CG10472 | CG9673 | FBpp0076774 | FBpp0308864 | RE65433p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | RE37738p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | 0.952 |
CG10472 | hiro | FBpp0076774 | FBpp0072505 | RE65433p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | GH21114p; Serine-type carboxypeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase S10 family. | 0.915 |
CG10472 | lambdaTry | FBpp0076774 | FBpp0087222 | RE65433p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | Trypsin-lambda; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | 0.821 |
CG10472 | sphe | FBpp0076774 | FBpp0074137 | RE65433p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | Spheroide (sphe) encodes a serine protein homologue, a serine protease with no catalytic activity. | 0.813 |
CG4653 | CG10472 | FBpp0074095 | FBpp0076774 | Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | RE65433p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | 0.868 |
CG4653 | CG9673 | FBpp0074095 | FBpp0308864 | Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | RE37738p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | 0.879 |
CG4653 | SPE | FBpp0074095 | FBpp0083832 | Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | Spaetzle-processing enzyme heavy chain; Endopeptidase which plays a key role in innate immunity by cleaving Tl ligand spz and thereby activating the Toll pathway in response to fungal and Gram-positive bacterial infections. Acts downstream of pathogen recognition receptors PGRP-SA and GNBP1 and protease grass in response to Gram-positive bacterial infection. Acts downstream of protease psh in response to fungal infection. Belongs to the peptidase S1 family. CLIP subfamily. | 0.497 |
CG4653 | hiro | FBpp0074095 | FBpp0072505 | Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | GH21114p; Serine-type carboxypeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase S10 family. | 0.446 |
CG4653 | lambdaTry | FBpp0074095 | FBpp0087222 | Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | Trypsin-lambda; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | 0.721 |
CG4653 | sphe | FBpp0074095 | FBpp0074137 | Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | Spheroide (sphe) encodes a serine protein homologue, a serine protease with no catalytic activity. | 0.857 |
CG9673 | CG10472 | FBpp0308864 | FBpp0076774 | RE37738p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | RE65433p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | 0.952 |
CG9673 | CG4653 | FBpp0308864 | FBpp0074095 | RE37738p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | 0.879 |
CG9673 | hiro | FBpp0308864 | FBpp0072505 | RE37738p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | GH21114p; Serine-type carboxypeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase S10 family. | 0.753 |
CG9673 | lambdaTry | FBpp0308864 | FBpp0087222 | RE37738p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | Trypsin-lambda; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | 0.844 |
CG9673 | sphe | FBpp0308864 | FBpp0074137 | RE37738p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | Spheroide (sphe) encodes a serine protein homologue, a serine protease with no catalytic activity. | 0.864 |
SPE | CG4653 | FBpp0083832 | FBpp0074095 | Spaetzle-processing enzyme heavy chain; Endopeptidase which plays a key role in innate immunity by cleaving Tl ligand spz and thereby activating the Toll pathway in response to fungal and Gram-positive bacterial infections. Acts downstream of pathogen recognition receptors PGRP-SA and GNBP1 and protease grass in response to Gram-positive bacterial infection. Acts downstream of protease psh in response to fungal infection. Belongs to the peptidase S1 family. CLIP subfamily. | Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. | 0.497 |
SPE | modSP | FBpp0083832 | FBpp0082798 | Spaetzle-processing enzyme heavy chain; Endopeptidase which plays a key role in innate immunity by cleaving Tl ligand spz and thereby activating the Toll pathway in response to fungal and Gram-positive bacterial infections. Acts downstream of pathogen recognition receptors PGRP-SA and GNBP1 and protease grass in response to Gram-positive bacterial infection. Acts downstream of protease psh in response to fungal infection. Belongs to the peptidase S1 family. CLIP subfamily. | Modular serine protease non-catalytic chain; Serine protease that plays a key role in innate immunity by activating the Toll pathway in response to infection with Gram-positive bacteria and fungi. During Gram- positive infection, acts downstream of PGRP-SA and upstream of Grass and Spz, and therefore appears to function in a pathway that links detection of Gram-positive lysine-type peptidoglycans to Toll activation. Functions in a separate pathway to the psh-mediated activation of the Toll pathway. Belongs to the peptidase S1 family. | 0.855 |
SPE | sphe | FBpp0083832 | FBpp0074137 | Spaetzle-processing enzyme heavy chain; Endopeptidase which plays a key role in innate immunity by cleaving Tl ligand spz and thereby activating the Toll pathway in response to fungal and Gram-positive bacterial infections. Acts downstream of pathogen recognition receptors PGRP-SA and GNBP1 and protease grass in response to Gram-positive bacterial infection. Acts downstream of protease psh in response to fungal infection. Belongs to the peptidase S1 family. CLIP subfamily. | Spheroide (sphe) encodes a serine protein homologue, a serine protease with no catalytic activity. | 0.936 |
SPE | sphinx1 | FBpp0083832 | FBpp0289592 | Spaetzle-processing enzyme heavy chain; Endopeptidase which plays a key role in innate immunity by cleaving Tl ligand spz and thereby activating the Toll pathway in response to fungal and Gram-positive bacterial infections. Acts downstream of pathogen recognition receptors PGRP-SA and GNBP1 and protease grass in response to Gram-positive bacterial infection. Acts downstream of protease psh in response to fungal infection. Belongs to the peptidase S1 family. CLIP subfamily. | Sphinx1 (sphinx1) encodes a protein related to the serine protease homolog, which is strongly expressed in the male accessory gland. | 0.951 |