STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ms(3)76CcMale sterile (3) 76Cc; It is involved in the biological process described with: spermatid differentiation. (1174 aa)    
Predicted Functional Partners:
Rcd7
Reduction in Cnn dots 7, isoform A; It is involved in the biological process described with: spermatogenesis; centrosome separation.
   
 
 0.927
ms(2)34Fe
Male sterile (2) 34Fe; It is involved in the biological process described with: spermatid differentiation.
   
  
 0.922
ATPsynbetaL
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.817
ms(2)35Ci
Male sterile (2) 35Ci, isoform A; It is involved in the biological process described with: spermatid differentiation.
   
  
 0.691
CG14305
AT25266p; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: intracellular signal transduction; protein phosphorylation.
   
 
 0.471
CG3222
Uncharacterized protein.
   
   0.458
ms(3)76Ca
Male sterile (3) 76Ca.
   
   0.443
CG31244
MIP05121p; Protein phosphatase 1 binding.
   
    0.439
Lrrk
Leucine-rich repeat kinase (Lrrk) encodes a large Ser/Thr kinase involved in mRNA translational control, cytoskeleton regulation, vesicle trafficking, autophagy, and immune response.
    
 
 0.419
twe
Twine (twe) encodes a putative tyrosine phosphatase. It regulates the meiotic cell cycle and contributes to spermatogenesis.
    
 
 0.402
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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