STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NaxdATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (300 aa)    
Predicted Functional Partners:
Naxe
NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.
  
  
 0.830
CG32554
Uncharacterized protein.
      
 0.670
CG6073
Protein HGH1 homolog; Belongs to the HGH1 family.
      
 0.670
CG17249
LD14179p; It is involved in the biological process described with: mitotic cell cycle checkpoint.
   
  
 0.669
CG14286
UPF0488 protein CG14286; Belongs to the UPF0488 family.
   
  
 0.666
CG13016
FI21814p1.
   
  
 0.662
CG12975
Multifunctional methyltransferase subunit TRM112-like protein; Acts as an activator of both RNA and protein methyltransferases.
   
  
 0.659
CG11788
IP10727p; DNA clamp loader activity. It is involved in the biological process described with: regulation of DNA replication; maintenance of mitotic sister chromatid cohesion.
   
  
 0.655
Pgm1
Phosphoglucomutase; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family.
 
 
    0.642
RnrL
Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
  
 0.640
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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