STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG6652GH21622p; It is involved in the biological process described with: intraciliary transport. (604 aa)    
Predicted Functional Partners:
Fam92
GH04442p; It is involved in the biological process described with: negative regulation of protein secretion.
      
 0.912
DZIP1
Uncharacterized protein, isoform A; Nucleic acid binding. It is involved in the biological process described with: cilium assembly.
   
 
 0.860
Mks1
Meckel syndrome type 1 protein homolog; Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia. Required for ciliary structure and function.
   
  
 0.834
CG3213
FI13205p.
   
   0.733
dila
Centrosomal protein of 131 kDa; Cilium-specific protein with a role in cilium/flagellum formation. May be involved in transport of components into the growing cilium. In germ cells and sensory neurons, plays a role with Cby in the building of the transition zone necessary for the formation of the ciliary cap and for the correct elongation of the axoneme.
   
 
 0.711
Klp59D
Kinesin-like protein at 59D (Klp59D) encodes a kinesin involved in the regulation spindle microtubule dynamics and sperm ciliogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.701
cep290
Centrosomal protein cep290; Essential for ciliogenesis in sensory neurons and germ cells. During neuron and spermatocyte ciliogenesis, plays a role in transition zone assembly where it is required for the formation of diverse connections between microtubules and between microtubules and the membrane.
   
  
 0.696
CG8564
Uncharacterized protein, isoform C; Zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis.
   
    0.660
B9d2
B9 domain-containing protein 2; Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia. Has a role in ciliary structure and function.
   
  
 0.612
ms(3)76Ca
Male sterile (3) 76Ca.
   
   0.585
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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