STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GlcAT-PGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase P; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins. Enzyme has a broad specificity. (479 aa)    
Predicted Functional Partners:
C1GalTA
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Core 1 Galactosyltransferase A (C1GalTA) encodes a protein that exhibits strong core 1beta1,3GalT activity, and is involved in the synthesis of T antigen in hemocytes. Its roles include hematopoietic stem cell maintenance, neural network and neuromuscular junction formation.
   
  
 0.848
CG42272
Uncharacterized protein, isoform C.
      
 0.791
CG14142
Uncharacterized protein, isoform B; Cysteine-type carboxypeptidase activity; Lys48-specific deubiquitinase activity.
      
 0.657
beta4GalT7
Beta-4-galactosyltransferase 7 (beta4GalT7) encodes an enzyme that transfers a Gal to the Xyl-O-Ser in the tetrasaccharide structure of the protein-linkage region of glycosaminoglycans (GAGs). It is involved in Hh and Dpp signaling pathways mediated by GAGs in development.
   
  
 0.652
GlcAT-I
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase I; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates; Belongs to the glycosyltransferase 43 family.
  
  
0.621
brv3
Brivido-3, isoform C; Calcium ion binding; calcium channel activity. It is involved in the biological process described with: calcium ion transport; detection of mechanical stimulus; response to cold.
      
 0.606
scaf6
SR-related CTD associated factor 6, isoform A; RNA binding. It is involved in the biological process described with: cellular calcium ion homeostasis; RNA processing.
      
 0.601
Tsp5D
Tetraspanin.
      
 0.601
Ttd14
TRPL translocation defect protein 14; GTP-binding protein which is required for the light-dependent internalization of the TRPL ion channel from the rhabdomere on the apical surface of photoreceptor cells to the cell body and for the recycling of TRPL back to the rhabdomere in the dark. Binds to 3- phosphoinositide (PtdIns(3)P) and phosphatic acid and so may interact with membranes, particularly the early endosome membrane where PtdIns(3)P is predominantly localized. Plays a role in preventing photoreceptor degeneration.
      
 0.548
Ugt304A1
UDP-glycosyltransferase family 304 member A1; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity.
      
 0.539
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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