node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG5235 | l(3)mbn | FBpp0075252 | FBpp0076770 | MOXD1 homolog 1; Copper ion binding; dopamine beta-monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen. It is involved in the biological process described with: oxidation-reduction process; norepinephrine biosynthetic process; octopamine biosynthetic process; dopamine catabolic process. | Protein lethal(3)malignant blood neoplasm 1; Lethal (3) malignant blood neoplasm (l(3)mbn) is a tumor suppressor gene with mutants showing abnormal proliferation of blood cells, differentiation of lamellocytes and melanotic nodule formation in the larva. | 0.658 |
CG5235 | tna | FBpp0075252 | FBpp0423259 | MOXD1 homolog 1; Copper ion binding; dopamine beta-monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen. It is involved in the biological process described with: oxidation-reduction process; norepinephrine biosynthetic process; octopamine biosynthetic process; dopamine catabolic process. | Tonalli, isoform B; Tonalli (tna) is an essential gene that encodes several isoforms, including Tna-A, which physically associates with subunits of the Brahma chromatin remodeling complex and is involved in transcriptional activation. | 0.669 |
PCNA | PCNA2 | FBpp0085619 | FBpp0080803 | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | Proliferating cell nuclear antigen 2; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. May function independently of PCNA during DNA repair. | 0.929 |
PCNA | Rad60 | FBpp0085619 | FBpp0083780 | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | Uncharacterized protein CG4449; It is involved in the biological process described with: double-strand break repair via homologous recombination. | 0.820 |
PCNA | lwr | FBpp0085619 | FBpp0301731 | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | Lesswright (lwr) encodes Ubc9, a SUMO conjugating enzyme that accepts SUMO from the SUMO activating enzyme and hands it off to the SUMO conjugation target. It has documented biological functions in innate immunity, meiosis, and anterior patterning of the embryo. | 0.891 |
PCNA | smt3 | FBpp0085619 | FBpp0078984 | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | Small ubiquitin-related modifier; Smt3 (smt3) encodes the only Drosophila SUMO family protein. It is required for embryonic patterning and mitosis. It may also have roles in wing patterning, Dpp signaling, and Ras/MAPK signaling. It localizes to the nucleus during interphase and to the kinetochores and midbodies during mitosis; Belongs to the ubiquitin family. SUMO subfamily. | 0.928 |
PCNA | tna | FBpp0085619 | FBpp0423259 | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | Tonalli, isoform B; Tonalli (tna) is an essential gene that encodes several isoforms, including Tna-A, which physically associates with subunits of the Brahma chromatin remodeling complex and is involved in transcriptional activation. | 0.708 |
PCNA2 | PCNA | FBpp0080803 | FBpp0085619 | Proliferating cell nuclear antigen 2; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. May function independently of PCNA during DNA repair. | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | 0.929 |
PCNA2 | Rad60 | FBpp0080803 | FBpp0083780 | Proliferating cell nuclear antigen 2; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. May function independently of PCNA during DNA repair. | Uncharacterized protein CG4449; It is involved in the biological process described with: double-strand break repair via homologous recombination. | 0.817 |
PCNA2 | lwr | FBpp0080803 | FBpp0301731 | Proliferating cell nuclear antigen 2; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. May function independently of PCNA during DNA repair. | Lesswright (lwr) encodes Ubc9, a SUMO conjugating enzyme that accepts SUMO from the SUMO activating enzyme and hands it off to the SUMO conjugation target. It has documented biological functions in innate immunity, meiosis, and anterior patterning of the embryo. | 0.883 |
PCNA2 | smt3 | FBpp0080803 | FBpp0078984 | Proliferating cell nuclear antigen 2; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. May function independently of PCNA during DNA repair. | Small ubiquitin-related modifier; Smt3 (smt3) encodes the only Drosophila SUMO family protein. It is required for embryonic patterning and mitosis. It may also have roles in wing patterning, Dpp signaling, and Ras/MAPK signaling. It localizes to the nucleus during interphase and to the kinetochores and midbodies during mitosis; Belongs to the ubiquitin family. SUMO subfamily. | 0.895 |
PCNA2 | tna | FBpp0080803 | FBpp0423259 | Proliferating cell nuclear antigen 2; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. May function independently of PCNA during DNA repair. | Tonalli, isoform B; Tonalli (tna) is an essential gene that encodes several isoforms, including Tna-A, which physically associates with subunits of the Brahma chromatin remodeling complex and is involved in transcriptional activation. | 0.708 |
Rad60 | PCNA | FBpp0083780 | FBpp0085619 | Uncharacterized protein CG4449; It is involved in the biological process described with: double-strand break repair via homologous recombination. | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | 0.820 |
Rad60 | PCNA2 | FBpp0083780 | FBpp0080803 | Uncharacterized protein CG4449; It is involved in the biological process described with: double-strand break repair via homologous recombination. | Proliferating cell nuclear antigen 2; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. May function independently of PCNA during DNA repair. | 0.817 |
Rad60 | Top1 | FBpp0083780 | FBpp0099689 | Uncharacterized protein CG4449; It is involved in the biological process described with: double-strand break repair via homologous recombination. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex (By similarity). Introduces a single-strand break via transesterification at a target site in duplex DNA (By similarity). The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand (By similarity). The free DNA strand then undergoes passage around the unb [...] | 0.622 |
Rad60 | lwr | FBpp0083780 | FBpp0301731 | Uncharacterized protein CG4449; It is involved in the biological process described with: double-strand break repair via homologous recombination. | Lesswright (lwr) encodes Ubc9, a SUMO conjugating enzyme that accepts SUMO from the SUMO activating enzyme and hands it off to the SUMO conjugation target. It has documented biological functions in innate immunity, meiosis, and anterior patterning of the embryo. | 0.936 |
Rad60 | smt3 | FBpp0083780 | FBpp0078984 | Uncharacterized protein CG4449; It is involved in the biological process described with: double-strand break repair via homologous recombination. | Small ubiquitin-related modifier; Smt3 (smt3) encodes the only Drosophila SUMO family protein. It is required for embryonic patterning and mitosis. It may also have roles in wing patterning, Dpp signaling, and Ras/MAPK signaling. It localizes to the nucleus during interphase and to the kinetochores and midbodies during mitosis; Belongs to the ubiquitin family. SUMO subfamily. | 0.612 |
Rad60 | tna | FBpp0083780 | FBpp0423259 | Uncharacterized protein CG4449; It is involved in the biological process described with: double-strand break repair via homologous recombination. | Tonalli, isoform B; Tonalli (tna) is an essential gene that encodes several isoforms, including Tna-A, which physically associates with subunits of the Brahma chromatin remodeling complex and is involved in transcriptional activation. | 0.814 |
Sry-beta | tna | FBpp0312401 | FBpp0423259 | Serendipity locus protein beta; Binds to the consensus DNA sequence 5'-YCAGAGATGCGCA-3'. | Tonalli, isoform B; Tonalli (tna) is an essential gene that encodes several isoforms, including Tna-A, which physically associates with subunits of the Brahma chromatin remodeling complex and is involved in transcriptional activation. | 0.674 |
Sry-delta | tna | FBpp0084924 | FBpp0423259 | Serendipity locus protein delta; Transcriptional activator that controls bicoid gene expression during oogenesis. Found in transcriptionally active cells. Binds to specific sites on polytene chromosomes of third instar larvae. Binds to the consensus DNA sequence 5'-YTAGAGATGGRAA-3'. | Tonalli, isoform B; Tonalli (tna) is an essential gene that encodes several isoforms, including Tna-A, which physically associates with subunits of the Brahma chromatin remodeling complex and is involved in transcriptional activation. | 0.609 |