STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG6576IP10051p; poly(A)-specific ribonuclease activity. It is involved in the biological process described with: negative regulation of translation; nuclear-transcribed mRNA poly(A) tail shortening; regulation of stem cell population maintenance. (267 aa)    
Predicted Functional Partners:
CG34034
Uncharacterized protein; It is involved in the biological process described with: multicellular organism reproduction.
   
  
 0.916
Not1
Not1, isoform H; Not1 (Not1) encodes a poly(A)-specific ribonuclease involved in translation inhibition and ovarian follicle cell development.
   
 0.900
Pop2
Pop2, isoform E; Pop2 (Pop2) encodes a poly(A)-specific ribonuclease involved in translation inhibition.
   
 0.899
Not3
CCR4-NOT transcription complex subunit 3 (Not3) encodes a poly(A)-specific ribonuclease involved in translation inhibition.
    
 0.896
Cnot4
CCR4-NOT transcription complex subunit 4 (Cnot4) encodes a positive regulator of the Jak/Stat pathway which acts by stabilizing the DNA binding of the product of Stat92E.
    
 0.882
CG31176
FI03584p.
      
 0.840
glec
Gliolectin (glec) encodes a member of carbohydrate-binding proteins. glec product regulates glia-glia and glia-neuron interactions during neurogenesis and positively regulates Notch pathway during the specification of vein and intervein regions in wing imaginal discs.
      
 0.835
CG14817
GEO02601p1; Structural constituent of ribosome. It is involved in the biological process described with: translation.
      
 0.791
CG9578
HL08141p; It is involved in the biological process described with: DNA damage checkpoint; TOR signaling; regulation of phosphoprotein phosphatase activity; signal transduction.
      
 0.790
CG31142
GEO07715p1.
      
 0.790
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.