STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
foiZinc transporter foi; Required for the normal migration of longitudinal and peripheral glial cells. During larval development, required for the migration of the subretinal glia into the eye disk. During embryonic development, also controls the migration of muscle cells toward their attachment sites. Required in the mesoderm for the correct morphogenesis of embryonic gonad and for tracheal branch fusion during tracheal development. Shg may be cooperating with foi to mediate a common mechanism for gonad and tracheal morphogenesis. Acts as a zinc transporter in both yeast and mammalian cells. (706 aa)    
Predicted Functional Partners:
CG14629
GH18858p.
      
 0.842
Zip71B
Zinc/iron regulated transporter-related protein 71B (Zip71B) encodes a protein involved in zinc detoxification and zinc transmembrane import.
  
 
0.765
Zip42C.1
Zinc/iron regulated transporter-related protein 42C.1 (Zip42C.1) encodes a plasma membrane resident zinc transporter belonging to the Zinc-Iron Permease family. It works together with the products of Zip42C.2 and Zip89B in dietary zinc absorption.
   
 0.703
Zip89B
Zinc/iron regulated transporter-related protein 89B (Zip89B) encodes a protein involved in zinc detoxification and zinc transmembrane import.
   
 0.673
svr
Carboxypeptidase D; Required for the proper melanization and sclerotization of the cuticle; Belongs to the peptidase M14 family.
      
 0.666
Zip88E
Zinc/iron regulated transporter-related protein 88E; Zinc ion transmembrane transporter activity. It is involved in the biological process described with: zinc ion transmembrane transport.
   
 0.635
CG1572
LD04844p; It is involved in the biological process described with: positive regulation of hemocyte proliferation.
   
  
 0.634
ZnT86D
Zinc transporter 86D (ZnT86D) encodes a transporter involved in zinc detoxification.
  
 
 0.628
ZnT49B
Zinc transporter 49B, isoform B; Cation transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; cation transport.
     
 0.608
Zip42C.2
Zinc/iron regulated transporter-related protein 42C.2 (Zip42C.2) encodes a protein involved in zinc detoxification and zinc transmembrane import.
   
 0.607
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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