STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CdsAPhosphatidate cytidylyltransferase, photoreceptor-specific; CDP diglyceride synthetase (CdsA) is an enzyme for the synthesis of cytidine diphosphate diacylglycerol (CDP-DAG) from phosphatidic acid. CDP-DAG is the precursor of two phospholipids, phosphatidylinositol and phosphatidylglycerol. CdsA has roles in cell growth and lipid storage (447 aa)    
Predicted Functional Partners:
Pis
CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity. It is involved in the biological process described with: phospholipid biosynthetic process; phototransduction
  
 0.997
CG3812
1-acylglycerol-3-phosphate O-acyltransferase activity. It is involved in the biological process described with: phospholipid biosynthetic process; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
  
 
 0.990
CG7718
RE55033p; CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity. It is involved in the biological process described with: phospholipid biosynthetic process
  
 
 0.988
Dgk
Diacylglycerol kinase 1; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (By similarity). May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons
   
 
 0.985
CLS
Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions
  
 
 0.982
rdgA
Eye-specific diacylglycerol kinase; Required for the maintenance of phospholipid turnover within the photoreceptor; Belongs to the eukaryotic diacylglycerol kinase family
    
 0.982
fu12
1-acylglycerol-3-phosphate O-acyltransferase activity. It is involved in the biological process described with: phospholipid biosynthetic process; behavioral response to ethanol
  
 
 0.978
CG31140
Diacylglycerol binding; diacylglycerol kinase activity; NAD+ kinase activity. It is involved in the biological process described with: intracellular signal transduction; lateral inhibition; metabolic process; protein kinase C-activating G-protein coupled receptor signaling pathway; phosphorylation
   
 
 0.974
Dgkepsilon
Diacylglycerol binding; diacylglycerol kinase activity; NAD+ kinase activity. It is involved in the biological process described with: intracellular signal transduction; protein kinase C-activating G-protein coupled receptor signaling pathway; phosphorylation
   
 
 0.973
CG11426
Uncharacterized protein CG11426; Phosphatidate phosphatase activity. It is involved in the biological process described with: dephosphorylation; phototransduction
  
 
 0.957
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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