STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pop4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (206 aa)    
Predicted Functional Partners:
Pop1
Lethal (1) G0045; Ribonuclease P activity; ribonuclease MRP activity. It is involved in the biological process described with: tRNA processing; rRNA processing; tRNA 5'-leader removal; RNA phosphodiester bond hydrolysis, endonucleolytic.
   
 0.999
Pop5
Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
   
 0.999
Rpp30
RNaseP protein p30 (Rpp30) encodes a protein involved in tRNA processing.
   
 0.999
Rpp21
Uncharacterized protein, isoform A; Ribonuclease P activity. It is involved in the biological process described with: tRNA processing; tRNA 5'-leader removal.
    
 0.999
Rpp25
FI09323p; RNA binding; ribonuclease P activity. It is involved in the biological process described with: tRNA 5'-leader removal.
   
 0.995
Rpp20
Ribonuclease P protein subunit p20; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences (By similarity).
   
 0.991
hoip
NHP2-like protein 1 homolog; Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding (By similarity); Belongs to the eukaryotic ribosomal protein eL8 family.
   
 
 0.936
Rpp14a
Uncharacterized protein; Ribonuclease P activity. It is involved in the biological process described with: tRNA 5'-leader removal.
   
 
  0.902
Rpp14b
GEO10372p1; Ribonuclease P activity. It is involved in the biological process described with: tRNA 5'-leader removal.
     
  0.900
CG5645
Protein KRI1 homolog; It is involved in the biological process described with: endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); Belongs to the KRI1 family.
   
   0.886
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.