STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG6462Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. (319 aa)    
Predicted Functional Partners:
Unc-76
Unc-76, isoform A; Unc-76 (Unc-76) encodes a kinesin binding protein involved in axo-dendritic transport.
      
 0.626
unc-4
Homeobox protein unc-4; Unc-4 (unc-4) encodes a homeodomain transcription factor expressed in distinct subsets of neurons in the embryonic and post-embryonic CNS. It regulates neuronal development and differentiation at least in part via repressing the expression of HGTX. It contributes to neuronal specification and differentiation, specifically axonal pathfinding and axongenesis.
      
 0.603
CG3795
GH24985p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
     0.526
CG4271
Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis.
  
     0.511
CG18223
Uncharacterized protein, isoform A; It is involved in the biological process described with: proteolysis.
  
     0.492
CG4815
IP10137p; Serine-type endopeptidase activity. It is involved in the biological process described with: multicellular organism reproduction; proteolysis; Belongs to the peptidase S1 family.
  
     0.460
unc-119
Protein unc-119 homolog; Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization.
      
 0.442
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.