STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gammaTub23CTubulin gamma-1 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. (475 aa)    
Predicted Functional Partners:
Grip75
Gamma-tubulin complex component 4 homolog; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
   
 0.997
Grip91
Gamma-tubulin complex component 3; Gamma-tubulin ring protein 91 (Grip91) encodes a gamma-tubulin binding protein involved in male meiotic division and the organization of the meiotic spindle; Belongs to the TUBGCP family.
   
 0.995
Grip84
Gamma-tubulin complex component 2 homolog; Gamma-tubulin binding; microtubule minus-end binding.
   
 0.995
Grip128
Grip128 (Grip128) encodes a component of the Gamma-tubulin ring complex, which is a potent microtubule nucleator in eukaryotic cells essential for successful chromosome segregation and cell division.
   
 0.992
Grip163
Grip163 (Grip163) encodes a gamma-tubulin binding protein involved in the mitotic cell cycle.
   
 0.988
Grip71
Grip71; Gamma-tubulin binding. It is involved in the biological process described with: centrosome cycle; protein localization to centrosome; regulation of cell cycle; spindle assembly involved in female meiosis I; mitotic cell cycle.
   
 0.974
Mzt1
Mitotic spindle organizing protein 1; Gamma-tubulin binding. It is involved in the biological process described with: gamma-tubulin complex localization; microtubule nucleation by interphase microtubule organizing center; mitotic spindle assembly.
    
 0.960
CG7716
Gamma-tubulin complex component; Microtubule minus-end binding; gamma-tubulin binding. It is involved in the biological process described with: microtubule nucleation by interphase microtubule organizing center; meiotic cell cycle; cytoplasmic microtubule organization; mitotic cell cycle; spindle assembly.
   
 0.929
CG18109
GCP_N_terminal domain-containing protein; Gamma-tubulin binding; microtubule minus-end binding. It is involved in the biological process described with: spindle assembly; mitotic cell cycle; microtubule nucleation by interphase microtubule organizing center; cytoplasmic microtubule organization; meiotic cell cycle.
   
 0.917
Sas-4
Spindle assembly abnormal 4 (Sas-4) encodes a centriole protein that is essential for centriole assembly. It is recruited to centrioles through an interaction with the centriole protein encoded by ana2, and it helps recruit microtubules to the centriole.
   
 
 0.910
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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