STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG14339FI19356p1; It is involved in the biological process described with: metaphase/anaphase transition of mitotic cell cycle; cell division; anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; protein ubiquitination. (1017 aa)    
Predicted Functional Partners:
CG18155
MIP16841p; Very long-chain fatty acid-CoA ligase activity; malonyl-CoA synthetase activity; CoA-ligase activity. It is involved in the biological process described with: fatty acid biosynthetic process; malonate catabolic process.
   
 
 0.921
Mst98Ca
Male-specific RNA 98Ca; It is involved in the biological process described with: spermatid development.
   
  
 0.846
CG2964
Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process.
  
 
 0.817
Lrrk
Leucine-rich repeat kinase (Lrrk) encodes a large Ser/Thr kinase involved in mRNA translational control, cytoskeleton regulation, vesicle trafficking, autophagy, and immune response.
  
 
 0.750
CG6661
GH20963p; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process.
   
  
 0.685
CG6845
Uncharacterized protein, isoform C.
      
 0.669
fzr2
Fizzy-related 2 (fzr2) is exclusively expressed in testis and encodes a protein that binds to the anaphase-promoting complex/cyclosome (APC/C). As for the related proteins encoded by fzr, fzy and cort, it activates the ubiquitin ligase activity of the APC/C and allows the recruitment of target proteins such as those encoded by CycA, CycB, CycB3 and pim.
   
  0.626
CG32181
AT19257p.
   
  
 0.619
CG34107
GEO10781p1.
   
 
 0.610
fzr
Fizzy-related, isoform A; Fizzy-related (fzr) encodes a protein that binds to the Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase to stimulate its activity during G1 phase.
    
  0.575
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.