STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MFS3Major facilitator superfamily transporter 3; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; anion transport. (512 aa)    
Predicted Functional Partners:
Ldh
Lactate dehydrogenase (Ldh) encodes a protein involved in myoblast fusion and somatic muscle development; Belongs to the LDH/MDH superfamily. LDH family.
   
    0.682
MFS16
Major facilitator superfamily transporter 16, isoform B; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport.
      
 0.675
CG13223
Uncharacterized protein; Calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential; cation transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; cellular calcium ion homeostasis; cation transport; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.668
CG1368
Uncharacterized protein; RNA polymerase II core promoter sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; transcription coactivator activity. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II.
   
  
 0.658
CG7882
IP16073p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
      
 0.601
Tret1-1
Facilitated trehalose transporter Tret1-1; Low-capacity facilitative transporter for trehalose. Does not transport maltose, sucrose or lactose. Mediates the bidirectional transfer of trehalose. Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
   
  
 0.555
CG11164
Uncharacterized protein, isoform A; RNA-DNA hybrid ribonuclease activity. It is involved in the biological process described with: ribonucleotide metabolic process; RNA catabolic process.
      
 0.547
nw
Narrow, isoform C; It is involved in the biological process described with: regulation of imaginal disc-derived wing size.
   
  
 0.539
CG13482
Uncharacterized protein.
      
 0.533
CG3777
SD17974p.
   
 
 0.497
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.