STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG11037CG11037 protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; multicellular organism reproduction; Belongs to the peptidase S1 family. (292 aa)    
Predicted Functional Partners:
Acp36DE
Accessory gland protein Acp36DE; Responsible for physiological and behavioral changes in mated female flies. Associates with sperm and localizes to specific regions of the female reproductive tract, including the sperm storage organs. It accelerates sperm accumulation into storage but does not mediate the entry of the first sperm into storage. Once sperm storage has initiated it seems to act as a guidance factor helping subsequent sperm move into storage, a corral concentrating sperm around the SSO entrances and/or a trigger for responses within the female that accelerate storage of sperm.
   
  
 0.933
CG9997
Uncharacterized protein, isoform A; CG9997 encodes a protein with homology to serine-type endopeptidases, but is not predicted to have catalytic activity due to mutations in its active site. It is produced in the male accessory gland and transferred to females during mating. In males, it is required for other seminal proteins to be transferred to mated females. In mated females, it is required for the binding of the product of SP to sperm and for the maintenance of long-term post-mating responses.
   
  
0.886
lectin-30A
Lectin-30A; Signaling receptor activity; galactose binding; carbohydrate binding. It is involved in the biological process described with: multicellular organism reproduction.
   
   0.874
Acp26Aa
Accessory gland protein 26Aa (Acp26Aa) encodes a protein synthesized in male accessory glands. It is transferred during mating to females where it induces an increase in ovulation by relaxing the oviduct via activation of octopaminergic signaling.
   
    0.854
CG17472
GEO08953p1; It is involved in the biological process described with: multicellular organism reproduction.
   
    0.851
Spn28F
Serpin 28F (Spn28F) encodes a predicted serine protease inhibitor. It is expressed in the male accessory glands and transferred to females during mating.
   
   0.848
Acp26Ab
Accessory gland protein 26Ab (Acp26Ab) encodes a peptide that is produced by male accessory glands and transferred to females during mating.
   
    0.846
lectin-29Ca
Lectin-29Ca; Carbohydrate binding; galactose binding. It is involved in the biological process described with: multicellular organism reproduction.
   
   0.844
Spn38F
Serpin 38F (Spn38F) encodes a predicted serine endopeptidase inhibitor. It is expressed in the male accessory glands and transferred to females during mating. Spn38F ectopic expression in females provides anti-microbial protection.
   
   0.843
aqrs
Aquarius (aqrs) encodes a predicted serine protease produced by the male accessory glands and transferred to females during mating. It is required for the binding of the product of SP to sperm and for the transfer of the products of lectin-46Ca and lectin-46Cb to females during mating.
   
    0.842
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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