Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DNApol-delta | DNApol-eta | FBpp0075277 | FBpp0078142 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | 0.897 |
| DNApol-delta | DNApol-zeta | FBpp0075277 | FBpp0087907 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | DNA polymerase zeta catalytic subunit; As the catalytic subunit of the DNA polymerase zeta complex, plays a crucial role in translesion DNA synthesis (TLS) and various DNA repair mechanisms. Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase eta to initiate repair synthesis which is completed by end joining or another polymerase that can bind and reinitiate synthesis. May participate in the Rrp1- dependent base excision repair (BER) pathway r [...] | 0.960 |
| DNApol-delta | PCNA | FBpp0075277 | FBpp0085619 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | 0.980 |
| DNApol-delta | PCNA2 | FBpp0075277 | FBpp0080803 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | Proliferating cell nuclear antigen 2; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. May function independently of PCNA during DNA repair. | 0.971 |
| DNApol-delta | Rev1 | FBpp0075277 | FBpp0072456 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | DNA repair protein Rev1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents (By similarity). During homologous recombination (HR) repair of DNA double-strand breaks (DSBs) regulates the extent of repair synthesis. Possibly recruits the DNA polymerase zeta complex or another translesion polymerase to earl [...] | 0.822 |
| DNApol-delta | Rev7 | FBpp0075277 | FBpp0078348 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | DNA polymerase zeta processivity subunit; As the accessory component of the DNA polymerase zeta complex, involved in translesion DNA synthesis (TLS) and various DNA repair mechanisms. Promotes the apurinic/apyrimidinic (AP) endonuclease activity of Rrp1 and is therefore likely to be involved in the base excision repair (BER) pathway responsible for repair of DNA lesions. It does not appear to influence the synthesis activity of the catalytic component Dmpol-zeta. | 0.977 |
| DNApol-delta | Uev1A | FBpp0075277 | FBpp0076859 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | Ubiquitin-conjugating enzyme variant 1A (Uev1A) encodes a conserved protein that contributes to ubiquitin conjugating enzyme activity, but not catalytically, since it lacks the conserved cysteine residue essential for ubiquitin conjugation. It regulates genomic integrity, IMD pathway-mediated innate immunity, JNK-pathway mediated cell death and tumor invasion. | 0.420 |
| DNApol-delta | spn-A | FBpp0075277 | FBpp0084955 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | DNA repair protein Rad51 homolog; Spindle A (spn-A) encodes a protein that forms a filament on single-stranded DNA, does a homology search of double-stranded DNA, and catalyzes strand exchange, swapping the single-strand DNA in and displacing the partner of the complementary strand. | 0.947 |
| DNApol-eta | DNApol-delta | FBpp0078142 | FBpp0075277 | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | 0.897 |
| DNApol-eta | DNApol-zeta | FBpp0078142 | FBpp0087907 | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | DNA polymerase zeta catalytic subunit; As the catalytic subunit of the DNA polymerase zeta complex, plays a crucial role in translesion DNA synthesis (TLS) and various DNA repair mechanisms. Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase eta to initiate repair synthesis which is completed by end joining or another polymerase that can bind and reinitiate synthesis. May participate in the Rrp1- dependent base excision repair (BER) pathway r [...] | 0.983 |
| DNApol-eta | PCNA | FBpp0078142 | FBpp0085619 | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | 0.960 |
| DNApol-eta | PCNA2 | FBpp0078142 | FBpp0080803 | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | Proliferating cell nuclear antigen 2; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. May function independently of PCNA during DNA repair. | 0.964 |
| DNApol-eta | Rchy1 | FBpp0078142 | FBpp0078901 | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | Ring finger and CHY zinc finger domain containing 1, isoform A; Ubiquitin protein ligase activity; zinc ion binding; ubiquitin-protein transferase activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; negative regulation of gliogenesis; protein ubiquitination. | 0.941 |
| DNApol-eta | Rev1 | FBpp0078142 | FBpp0072456 | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | DNA repair protein Rev1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents (By similarity). During homologous recombination (HR) repair of DNA double-strand breaks (DSBs) regulates the extent of repair synthesis. Possibly recruits the DNA polymerase zeta complex or another translesion polymerase to earl [...] | 0.991 |
| DNApol-eta | Rev7 | FBpp0078142 | FBpp0078348 | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | DNA polymerase zeta processivity subunit; As the accessory component of the DNA polymerase zeta complex, involved in translesion DNA synthesis (TLS) and various DNA repair mechanisms. Promotes the apurinic/apyrimidinic (AP) endonuclease activity of Rrp1 and is therefore likely to be involved in the base excision repair (BER) pathway responsible for repair of DNA lesions. It does not appear to influence the synthesis activity of the catalytic component Dmpol-zeta. | 0.942 |
| DNApol-eta | RpS27A | FBpp0078142 | FBpp0079606 | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involve [...] | 0.835 |
| DNApol-eta | Uev1A | FBpp0078142 | FBpp0076859 | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | Ubiquitin-conjugating enzyme variant 1A (Uev1A) encodes a conserved protein that contributes to ubiquitin conjugating enzyme activity, but not catalytically, since it lacks the conserved cysteine residue essential for ubiquitin conjugation. It regulates genomic integrity, IMD pathway-mediated innate immunity, JNK-pathway mediated cell death and tumor invasion. | 0.862 |
| DNApol-eta | spn-A | FBpp0078142 | FBpp0084955 | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | DNA repair protein Rad51 homolog; Spindle A (spn-A) encodes a protein that forms a filament on single-stranded DNA, does a homology search of double-stranded DNA, and catalyzes strand exchange, swapping the single-strand DNA in and displacing the partner of the complementary strand. | 0.853 |
| DNApol-zeta | DNApol-delta | FBpp0087907 | FBpp0075277 | DNA polymerase zeta catalytic subunit; As the catalytic subunit of the DNA polymerase zeta complex, plays a crucial role in translesion DNA synthesis (TLS) and various DNA repair mechanisms. Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase eta to initiate repair synthesis which is completed by end joining or another polymerase that can bind and reinitiate synthesis. May participate in the Rrp1- dependent base excision repair (BER) pathway r [...] | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | 0.960 |
| DNApol-zeta | DNApol-eta | FBpp0087907 | FBpp0078142 | DNA polymerase zeta catalytic subunit; As the catalytic subunit of the DNA polymerase zeta complex, plays a crucial role in translesion DNA synthesis (TLS) and various DNA repair mechanisms. Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase eta to initiate repair synthesis which is completed by end joining or another polymerase that can bind and reinitiate synthesis. May participate in the Rrp1- dependent base excision repair (BER) pathway r [...] | DNApol-eta; DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS). Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Inserts one or 2 nucleotide(s) opposite the lesion. During homologous recombination (HR) repair, has a overlapping role with the error-prone translesion polymerase DNApol-zeta/DNApolZ1 to initiate repair synthesis that is completed by end joining or another polymerase that can bind and reinitiate synthesis. Particularly important for the repair of UV-in [...] | 0.983 |
page 1 of 5