STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
jagnJagunal (jagn) encodes a conserved protein that is located in the endoplasmic reticulum membrane. It contributes to oocyte growth by organizing the endoplasmic reticulum. It is also involved in bristle growth. (197 aa)    
Predicted Functional Partners:
CG10208
RE64534p.
 
      0.830
Kr-h2
Krueppel homolog 2; Member of the dosage-dependent hierarchy effective upon white gene expression; Belongs to the PER33/POM33 family.
   
 
 0.691
CG16791
LP06548p.
      
 0.671
CG13192
IP10750p; It is involved in the biological process described with: social behavior.
   
  
 0.632
mRpL38
Mitochondrial ribosomal protein L38; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation.
   
  
 0.620
Surf4
Surfeit locus protein 4 homolog; Belongs to the SURF4 family.
   
 
 0.607
Rtnl1
Reticulon-like1 (Rtnl1) encodes a reticulon family member, with predicted intramembrane hairpin domains that can insert into the cytosolic face of the endoplasmic reticulum (ER), thereby curving it and promoting ER tubule formation. It is enriched on tubular ER, including axons and egg chamber fusomes.
   
  
 0.515
Sec61alpha
Sec61 alpha subunit (Sec61alpha) encodes a subunit of the the translocon, a protein-conducting channel that mediates the co-translational transport of nascent polypeptides into the endoplasmic reticulum. It is a subunit of the Sec61 heterotrimer that forms the core of translocon channel.
   
 
 0.505
fws
Conserved oligomeric Golgi complex subunit 5; Four way stop (fws) encodes a protein localised to the Golgi apparatus and involved in several aspects of spermatogenesis. Loss of function of fws causes failure of cleavage furrow ingression in dividing spermatocytes, as well as failure of cell elongation and disruption of the Golgi-based acroblast during spermatid differentiation.
      
 0.495
uzip
Unzipped (uzip) encodes a cell adhesion molecule that genetically interacts with CadN. Its biological function includes regulation of axon guidance.
      
 0.493
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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