STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG1236Uncharacterized protein; Glycerate dehydrogenase activity; glyoxylate reductase (NADP) activity; NAD binding; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; hydroxypyruvate reductase activity. It is involved in the biological process described with: oxidation-reduction process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (347 aa)    
Predicted Functional Partners:
Spat
Serine pyruvate aminotransferase (Spat) encodes an alanine-glyoxylate transaminase involved in glyoxylate catabolism.
  
 
 0.947
CG9886
Glycerate kinase activity. It is involved in the biological process described with: protein phosphorylation; Belongs to the glycerate kinase type-2 family.
 
 
 0.947
CG18003
L-lactate dehydrogenase activity; FMN binding; (S)-2-hydroxy-acid oxidase activity. It is involved in the biological process described with: lactate oxidation.
  
 
 0.944
Glo1
Glyoxalase 1; Lactoylglutathione lyase activity; metal ion binding. It is involved in the biological process described with: regulation of insulin receptor signaling pathway.
 
 0.914
Gip
Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.
  
 
 0.912
CG11291
Phosphoprotein phosphatase activity; phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; dephosphorylation; Belongs to the HAD-like hydrolase superfamily.
  
 
 0.910
CG32487
Uncharacterized protein; Phosphatase activity. It is involved in the biological process described with: dephosphorylation; Belongs to the HAD-like hydrolase superfamily.
  
 
 0.910
CG5567
FI11325p; Phosphatase activity; phosphoprotein phosphatase activity; alkaline phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; dephosphorylation.
  
 
 0.910
CG32488
GH05933p; Phosphatase activity. It is involved in the biological process described with: dephosphorylation; Belongs to the HAD-like hydrolase superfamily.
  
 
 0.910
CG5577
GH10306p; Phosphatase activity. It is involved in the biological process described with: dephosphorylation; Belongs to the HAD-like hydrolase superfamily.
  
 
 0.910
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.