STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rauRau, isoform A; Rau (rau) encodes a protein that sustains RTK signaling downstream of the product of htl or Egfr. This effect is mediated by the two Ras association (RA) domains that together show a binding preference for GTP-loaded Ras. rau depletion produces a rough eye phenotype and reduced differentiation of retinal wrapping glia. (430 aa)    
Predicted Functional Partners:
nmd
No mitochondrial derivative, isoform A; ATP binding. It is involved in the biological process described with: wing disc dorsal/ventral pattern formation; spermatid development; Belongs to the AAA ATPase family.
      
 0.670
CG11629
IP11623p1.
      
 0.660
CG3246
FI04421p; Lipid binding.
   
  
 0.614
CG8066
GEO08281p1; Cysteine-type endopeptidase inhibitor activity.
   
  
 0.607
CG1246
RE02644p.
      
 0.607
CG6337
RE20049p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family.
      
 0.607
Obp50e
Odorant-binding protein 50e; Odorant binding. It is involved in the biological process described with: sensory perception of chemical stimulus.
      
 0.605
CG14762
MIP14966p.
      
 0.602
CG15283
IP09907p; It is involved in the biological process described with: mitochondrial respiratory chain complex II assembly.
      
 0.601
CG14756
RH66388p.
   
  
 0.544
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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