STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GaltProbable galactose-1-phosphate uridylyltransferase; UDP-glucose:hexose-1-phosphate uridylyltransferase activity; zinc ion binding. It is involved in the biological process described with: adult locomotory behavior; galactose homeostasis; galactose metabolic process (350 aa)    
Predicted Functional Partners:
Gale
UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...]
  
 0.999
Galk
Galactokinase, isoform A; ATP binding; galactokinase activity. It is involved in the biological process described with: carbohydrate phosphorylation; galactose metabolic process
 
 0.999
UGP
UGP, isoform A; UTP:glucose-1-phosphate uridylyltransferase activity. It is involved in the biological process described with: UDP-glucose metabolic process
   
 0.996
sgl
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate and heparan sulfate. Required for wingless signaling in different tissues; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family
   
 0.973
Pgm
Phosphoglucomutase; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family
  
  
 0.886
CG5068
Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated
      
 0.853
CG1129
Mannose-1-phosphate guanyltransferase beta; Mannose-1-phosphate guanylyltransferase activity. It is involved in the biological process described with: biosynthetic process
     
 0.802
CG8207
RE21160p; Mannose-1-phosphate guanylyltransferase activity. It is involved in the biological process described with: biosynthetic process
     
 0.790
CG3038
Hexosyltransferase; Transferase activity, transferring glycosyl groups; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity. It is involved in the biological process described with: protein glycosylation
      
 0.749
CG8417
Mannose-6-phosphate isomerase activity; zinc ion binding. It is involved in the biological process described with: GDP-mannose biosynthetic process; carbohydrate metabolic process
   
  
 0.743
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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