Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG11162 | CG17270 | FBpp0073642 | FBpp0083398 | Fatty acid hydroxylase domain-containing protein; C-4 methylsterol oxidase activity; oxidoreductase activity; iron ion binding. It is involved in the biological process described with: sterol biosynthetic process; oxidation-reduction process; Belongs to the sterol desaturase family. | GM10285p; Protein-macromolecule adaptor activity. | 0.968 |
| CG11162 | LBR | FBpp0073642 | FBpp0071630 | Fatty acid hydroxylase domain-containing protein; C-4 methylsterol oxidase activity; oxidoreductase activity; iron ion binding. It is involved in the biological process described with: sterol biosynthetic process; oxidation-reduction process; Belongs to the sterol desaturase family. | Lamin-B receptor; Anchors the lamina and the heterochromatin to the inner nuclear membrane; Belongs to the ERG4/ERG24 family. | 0.921 |
| CG11162 | Rca1 | FBpp0073642 | FBpp0078970 | Fatty acid hydroxylase domain-containing protein; C-4 methylsterol oxidase activity; oxidoreductase activity; iron ion binding. It is involved in the biological process described with: sterol biosynthetic process; oxidation-reduction process; Belongs to the sterol desaturase family. | Regulator of cyclin A1 (Rca1) encodes an anaphase-promoting complex/cyclosome inhibitor. It contributes to mitotic G1/S transition and cyclin degradation. | 0.837 |
| CG17270 | CG11162 | FBpp0083398 | FBpp0073642 | GM10285p; Protein-macromolecule adaptor activity. | Fatty acid hydroxylase domain-containing protein; C-4 methylsterol oxidase activity; oxidoreductase activity; iron ion binding. It is involved in the biological process described with: sterol biosynthetic process; oxidation-reduction process; Belongs to the sterol desaturase family. | 0.968 |
| CG17270 | CG1998 | FBpp0083398 | FBpp0073618 | GM10285p; Protein-macromolecule adaptor activity. | RE26969p; Iron ion binding; oxidoreductase activity; C-4 methylsterol oxidase activity. It is involved in the biological process described with: sterol biosynthetic process; oxidation-reduction process; Belongs to the sterol desaturase family. | 0.969 |
| CG17270 | LBR | FBpp0083398 | FBpp0071630 | GM10285p; Protein-macromolecule adaptor activity. | Lamin-B receptor; Anchors the lamina and the heterochromatin to the inner nuclear membrane; Belongs to the ERG4/ERG24 family. | 0.930 |
| CG17270 | Rca1 | FBpp0083398 | FBpp0078970 | GM10285p; Protein-macromolecule adaptor activity. | Regulator of cyclin A1 (Rca1) encodes an anaphase-promoting complex/cyclosome inhibitor. It contributes to mitotic G1/S transition and cyclin degradation. | 0.897 |
| CG1998 | CG17270 | FBpp0073618 | FBpp0083398 | RE26969p; Iron ion binding; oxidoreductase activity; C-4 methylsterol oxidase activity. It is involved in the biological process described with: sterol biosynthetic process; oxidation-reduction process; Belongs to the sterol desaturase family. | GM10285p; Protein-macromolecule adaptor activity. | 0.969 |
| CG1998 | LBR | FBpp0073618 | FBpp0071630 | RE26969p; Iron ion binding; oxidoreductase activity; C-4 methylsterol oxidase activity. It is involved in the biological process described with: sterol biosynthetic process; oxidation-reduction process; Belongs to the sterol desaturase family. | Lamin-B receptor; Anchors the lamina and the heterochromatin to the inner nuclear membrane; Belongs to the ERG4/ERG24 family. | 0.925 |
| CG1998 | Rca1 | FBpp0073618 | FBpp0078970 | RE26969p; Iron ion binding; oxidoreductase activity; C-4 methylsterol oxidase activity. It is involved in the biological process described with: sterol biosynthetic process; oxidation-reduction process; Belongs to the sterol desaturase family. | Regulator of cyclin A1 (Rca1) encodes an anaphase-promoting complex/cyclosome inhibitor. It contributes to mitotic G1/S transition and cyclin degradation. | 0.837 |
| Cul1 | CycA | FBpp0087922 | FBpp0075807 | Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...] | G2/mitotic-specific cyclin-A; Cyclin A (CycA) encodes a protein that binds to the product of Cdk1, thereby promoting Cdk1's protein kinase activity. The CycA-Cdk1 complex controls important aspects of progression through the cell cycle, including entry into mitosis. During the G2 phase, this complex is important for prevention of premature DNA re-replication. During mitosis and G1, the product of CycA is rapidly degraded (involving APC/C and the proteasome), resulting in inactivation of Cdk1 protein kinase activity. | 0.912 |
| Cul1 | Rca1 | FBpp0087922 | FBpp0078970 | Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...] | Regulator of cyclin A1 (Rca1) encodes an anaphase-promoting complex/cyclosome inhibitor. It contributes to mitotic G1/S transition and cyclin degradation. | 0.856 |
| Cul1 | SkpA | FBpp0087922 | FBpp0099971 | Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...] | SKP1-related A (SkpA) encodes a subunit of Skp, Cullin, F-box (SCF)-containing ubiquitin ligase complexes. It regulates centrosome duplication, chromatin condensation, cell cycle progression, cell polarity, dendrite pruning and endoreduplication. | 0.999 |
| Cul1 | fzr | FBpp0087922 | FBpp0070654 | Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...] | Fizzy-related, isoform A; Fizzy-related (fzr) encodes a protein that binds to the Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase to stimulate its activity during G1 phase. | 0.571 |
| Cul1 | fzy | FBpp0087922 | FBpp0080391 | Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...] | FI02843p; Fizzy (fzy) encodes WD40 domain protein required for the full ubiquitin ligase activity of the anaphase-promoting complex/cyclosome (APC/C) in mitosis and meiosis. The product of fzy functions to target substrates for destruction and drive metaphase and anaphase transition. | 0.791 |
| Cul1 | polo | FBpp0087922 | FBpp0074608 | Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...] | Serine/threonine-protein kinase polo; May play a role in regulating both nuclear and cytoplasmic aspects of the mitotic cycle. Regulates localization of the augmin complex during mitosis by ensuring its location on mitotic spindles. Also regulates augmin complex localization during male meiosis by promoting its placement at kinetochores while preventing its association with spindle microtubules ; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. | 0.697 |
| CycA | Cul1 | FBpp0075807 | FBpp0087922 | G2/mitotic-specific cyclin-A; Cyclin A (CycA) encodes a protein that binds to the product of Cdk1, thereby promoting Cdk1's protein kinase activity. The CycA-Cdk1 complex controls important aspects of progression through the cell cycle, including entry into mitosis. During the G2 phase, this complex is important for prevention of premature DNA re-replication. During mitosis and G1, the product of CycA is rapidly degraded (involving APC/C and the proteasome), resulting in inactivation of Cdk1 protein kinase activity. | Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...] | 0.912 |
| CycA | Rca1 | FBpp0075807 | FBpp0078970 | G2/mitotic-specific cyclin-A; Cyclin A (CycA) encodes a protein that binds to the product of Cdk1, thereby promoting Cdk1's protein kinase activity. The CycA-Cdk1 complex controls important aspects of progression through the cell cycle, including entry into mitosis. During the G2 phase, this complex is important for prevention of premature DNA re-replication. During mitosis and G1, the product of CycA is rapidly degraded (involving APC/C and the proteasome), resulting in inactivation of Cdk1 protein kinase activity. | Regulator of cyclin A1 (Rca1) encodes an anaphase-promoting complex/cyclosome inhibitor. It contributes to mitotic G1/S transition and cyclin degradation. | 0.872 |
| CycA | SkpA | FBpp0075807 | FBpp0099971 | G2/mitotic-specific cyclin-A; Cyclin A (CycA) encodes a protein that binds to the product of Cdk1, thereby promoting Cdk1's protein kinase activity. The CycA-Cdk1 complex controls important aspects of progression through the cell cycle, including entry into mitosis. During the G2 phase, this complex is important for prevention of premature DNA re-replication. During mitosis and G1, the product of CycA is rapidly degraded (involving APC/C and the proteasome), resulting in inactivation of Cdk1 protein kinase activity. | SKP1-related A (SkpA) encodes a subunit of Skp, Cullin, F-box (SCF)-containing ubiquitin ligase complexes. It regulates centrosome duplication, chromatin condensation, cell cycle progression, cell polarity, dendrite pruning and endoreduplication. | 0.925 |
| CycA | fzr | FBpp0075807 | FBpp0070654 | G2/mitotic-specific cyclin-A; Cyclin A (CycA) encodes a protein that binds to the product of Cdk1, thereby promoting Cdk1's protein kinase activity. The CycA-Cdk1 complex controls important aspects of progression through the cell cycle, including entry into mitosis. During the G2 phase, this complex is important for prevention of premature DNA re-replication. During mitosis and G1, the product of CycA is rapidly degraded (involving APC/C and the proteasome), resulting in inactivation of Cdk1 protein kinase activity. | Fizzy-related, isoform A; Fizzy-related (fzr) encodes a protein that binds to the Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase to stimulate its activity during G1 phase. | 0.989 |
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