STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FucTBAlpha-(1,3)-fucosyltransferase B; Alpha-(1->3)-fucosyltransferase activity. It is involved in the biological process described with: fucosylation; protein glycosylation; Belongs to the glycosyltransferase 10 family. (444 aa)    
Predicted Functional Partners:
FucT6
Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. The addition is prevented if the GlcNAc residue is already fucosylated.
      
 0.921
Gmer
Probable GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction; Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
      
 0.741
FucTC
Fucosyltransferase activity; alpha-(1->3)-fucosyltransferase activity. It is involved in the biological process described with: fucosylation; protein glycosylation; Belongs to the glycosyltransferase 10 family.
  
  
0.683
FucTD
Alpha-(1->3)-fucosyltransferase activity. It is involved in the biological process described with: fucosylation; protein glycosylation.
   
 
0.658
FucTA
Glycoprotein 3-alpha-L-fucosyltransferase A; Alpha1,3-fucosyltransferase A (FucTA) encodes a Golgi fucosyltransferase that transfers fucose in alpha1,3-linkage to core N-acetylglucosamine residues of N-linked oligosaccharides. It is required for the synthesis of the anti-horseradish peroxidase epitope; Belongs to the glycosyltransferase 10 family.
     
0.617
CG15570
Uncharacterized protein.
      
 0.602
Mgat1
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat1) encodes an enzyme involved in the synthesis of paucimannose N-glycans. It is required in the CNS, with involvement in locomotion, brain development and lifespan.
   
  
 0.568
Sodh-2
Sorbitol dehydrogenase-2; L-iditol 2-dehydrogenase activity; zinc ion binding. It is involved in the biological process described with: oxidation-reduction process; sorbitol catabolic process.
      
 0.491
sPLA2
Secretory phospholipase A2, isoform A; Calcium-dependent phospholipase A2 activity. It is involved in the biological process described with: arachidonic acid secretion; phospholipid metabolic process.
      
 0.491
Inx3
Innexin 3 (Inx3) encodes a gap junction protein that can form heteromeric gap junction channels via interaction with the product of Inx2. Loss of Inx3 leads to the destabilization of the products of ogre, Inx2 and shg at the plasma membrane, suggesting that these four proteins form a complex.
      
 0.450
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.