STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brwlBrickwall, isoform A; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. (435 aa)    
Predicted Functional Partners:
CG11723
LD29420p; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
    
 
 0.838
CG1602
LD33878p; Sequence-specific DNA binding. It is involved in the biological process described with: regulation of gene expression; positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated.
      
 0.790
Asciz
ASCIZ zinc finger protein (Asciz) encodes a transcription factor that regulates the expression of ctp, which encodes a LC8 dynein light chain. The product of Asciz is involved in dynein motor functions, including mitotic chromosome segregation, and dynein-independent functions, such as patterning of cell cycles and apoptosis during development.
      
 0.721
CG15514
LD24318p; DNA binding.
   
 
 0.672
CG4617
LD46272p.
      
 0.663
CG1603
FI01116p; Transcription coactivator activity; nucleic acid binding. It is involved in the biological process described with: regulation of gene expression; positive regulation of transcription by RNA polymerase II.
   
  
 0.663
az2
RE20796p; RNA polymerase II regulatory region sequence-specific DNA binding; sequence-specific DNA binding; zinc ion binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated.
   
  
 0.627
CG8924
LD19131p; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
   
  
 0.626
hng1
CG9437 protein; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
    
 
 0.588
CG10949
GH22016p; It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
      
 0.548
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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