node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG31211 | Srp54 | FBpp0081954 | FBpp0079471 | Uncharacterized protein, isoform B. | LD29830p; Srp54 (Srp54) encodes a protein that regulates mRNA alternative splicing, the processing of the mRNA 3'-end and the selection of the transcriptional start site. | 0.889 |
CG6015 | Pabp2 | FBpp0083581 | FBpp0087863 | LD21931p; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. | Polyadenylate-binding protein 2; Involved in the 3'-end formation of mRNA precursors (pre- mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Binds to poly(A) and to poly(G) with high affinity. May protect the poly(A) tail from degradation (By similarity). Plays a role in the positive regulation of alpha-1,3 fucosylation, [...] | 0.800 |
CG6015 | Rbp1 | FBpp0083581 | FBpp0081754 | LD21931p; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. | RNA-binding protein 1; Contributes to the activation of female-specific DSX splicing in vivo by recognizing the RBP1 target sequences within the purine-rich polypyrimidine tract of the female-specific 3' splice site. Belongs to the splicing factor SR family. | 0.803 |
CG6015 | SC35 | FBpp0083581 | FBpp0297362 | LD21931p; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. | SR family splicing factor SC35 (SC35) encodes a mRNA binding protein that regulates mRNA alternative splicing, the processing of the mRNA 3'-end and the selection of the transcriptional start site. | 0.816 |
CG6015 | SF2 | FBpp0083581 | FBpp0293269 | LD21931p; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. | Splicing factor 2 (SF2) encodes a protein involved in alternative mRNA splicing, RNA export from the nucleus and the regulation of the RNA metabolism. | 0.859 |
CG6015 | Slu7 | FBpp0083581 | FBpp0084787 | LD21931p; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. | Pre-mRNA-splicing factor Slu7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. | 0.998 |
CG6015 | Srp54 | FBpp0083581 | FBpp0079471 | LD21931p; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. | LD29830p; Srp54 (Srp54) encodes a protein that regulates mRNA alternative splicing, the processing of the mRNA 3'-end and the selection of the transcriptional start site. | 0.838 |
CG6015 | U2af38 | FBpp0083581 | FBpp0305600 | LD21931p; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. | U2 small nuclear riboprotein auxiliary factor 38 (U2af38) encodes the small subunit of the pre-mRNA splicing factor complex U2AF. This heterodimeric complex binds to the intron pyrimidine tract and targets the product of snf to the branch site early in spliceosome assembly. The U2af38 product binds to the AG dinucleotide at the 3' splice site. | 0.892 |
Doa | Fst | FBpp0289029 | FBpp0081579 | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | LP07623p; Frost (Fst) encodes a potentially secreted protein that protects female reproduction after cold treatment. | 0.669 |
Doa | Rbp1 | FBpp0289029 | FBpp0081754 | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | RNA-binding protein 1; Contributes to the activation of female-specific DSX splicing in vivo by recognizing the RBP1 target sequences within the purine-rich polypyrimidine tract of the female-specific 3' splice site. Belongs to the splicing factor SR family. | 0.702 |
Doa | SC35 | FBpp0289029 | FBpp0297362 | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | SR family splicing factor SC35 (SC35) encodes a mRNA binding protein that regulates mRNA alternative splicing, the processing of the mRNA 3'-end and the selection of the transcriptional start site. | 0.597 |
Doa | SF2 | FBpp0289029 | FBpp0293269 | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | Splicing factor 2 (SF2) encodes a protein involved in alternative mRNA splicing, RNA export from the nucleus and the regulation of the RNA metabolism. | 0.604 |
Doa | Srp54 | FBpp0289029 | FBpp0079471 | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | LD29830p; Srp54 (Srp54) encodes a protein that regulates mRNA alternative splicing, the processing of the mRNA 3'-end and the selection of the transcriptional start site. | 0.903 |
Fst | Doa | FBpp0081579 | FBpp0289029 | LP07623p; Frost (Fst) encodes a potentially secreted protein that protects female reproduction after cold treatment. | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | 0.669 |
Fst | Srp54 | FBpp0081579 | FBpp0079471 | LP07623p; Frost (Fst) encodes a potentially secreted protein that protects female reproduction after cold treatment. | LD29830p; Srp54 (Srp54) encodes a protein that regulates mRNA alternative splicing, the processing of the mRNA 3'-end and the selection of the transcriptional start site. | 0.825 |
Pabp2 | CG6015 | FBpp0087863 | FBpp0083581 | Polyadenylate-binding protein 2; Involved in the 3'-end formation of mRNA precursors (pre- mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Binds to poly(A) and to poly(G) with high affinity. May protect the poly(A) tail from degradation (By similarity). Plays a role in the positive regulation of alpha-1,3 fucosylation, [...] | LD21931p; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. | 0.800 |
Pabp2 | Rbp1 | FBpp0087863 | FBpp0081754 | Polyadenylate-binding protein 2; Involved in the 3'-end formation of mRNA precursors (pre- mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Binds to poly(A) and to poly(G) with high affinity. May protect the poly(A) tail from degradation (By similarity). Plays a role in the positive regulation of alpha-1,3 fucosylation, [...] | RNA-binding protein 1; Contributes to the activation of female-specific DSX splicing in vivo by recognizing the RBP1 target sequences within the purine-rich polypyrimidine tract of the female-specific 3' splice site. Belongs to the splicing factor SR family. | 0.846 |
Pabp2 | SC35 | FBpp0087863 | FBpp0297362 | Polyadenylate-binding protein 2; Involved in the 3'-end formation of mRNA precursors (pre- mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Binds to poly(A) and to poly(G) with high affinity. May protect the poly(A) tail from degradation (By similarity). Plays a role in the positive regulation of alpha-1,3 fucosylation, [...] | SR family splicing factor SC35 (SC35) encodes a mRNA binding protein that regulates mRNA alternative splicing, the processing of the mRNA 3'-end and the selection of the transcriptional start site. | 0.837 |
Pabp2 | SF2 | FBpp0087863 | FBpp0293269 | Polyadenylate-binding protein 2; Involved in the 3'-end formation of mRNA precursors (pre- mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Binds to poly(A) and to poly(G) with high affinity. May protect the poly(A) tail from degradation (By similarity). Plays a role in the positive regulation of alpha-1,3 fucosylation, [...] | Splicing factor 2 (SF2) encodes a protein involved in alternative mRNA splicing, RNA export from the nucleus and the regulation of the RNA metabolism. | 0.909 |
Pabp2 | Slu7 | FBpp0087863 | FBpp0084787 | Polyadenylate-binding protein 2; Involved in the 3'-end formation of mRNA precursors (pre- mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Binds to poly(A) and to poly(G) with high affinity. May protect the poly(A) tail from degradation (By similarity). Plays a role in the positive regulation of alpha-1,3 fucosylation, [...] | Pre-mRNA-splicing factor Slu7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. | 0.803 |