STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LManIILysosomal alpha-mannosidase II (LManII) encodes a mannosyl-oligosaccharide 1,2-alpha-mannosidase involved in the degradation of asparagine-linked carbohydrates of glycoproteins. (1080 aa)    
Predicted Functional Partners:
alpha-Man-Ic
alpha-1,2-Mannosidase; Calcium ion binding; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. It is involved in the biological process described with: N-glycan processing; Belongs to the glycosyl hydrolase 47 family.
      
 0.698
CG7997
Alpha-galactosidase activity. It is involved in the biological process described with: glycosylceramide catabolic process; glycoside catabolic process; oligosaccharide metabolic process.
   
 
 0.626
CG4752
FI03324p; 5-oxoprolinase (ATP-hydrolyzing) activity. It is involved in the biological process described with: glutathione metabolic process.
      
 0.610
CG7519
RE39629p.
      
 0.602
CG2493
GH14278p; Dipeptidyl-peptidase activity; serine-type peptidase activity. It is involved in the biological process described with: proteolysis.
   
 
 0.602
CG33920
Uncharacterized protein.
      
 0.602
Cpr49Ab
Cuticular protein 49Ab; Structural constituent of cuticle; structural constituent of chitin-based larval cuticle. It is involved in the biological process described with: chitin-based cuticle development.
   
 
 0.542
CG7173
Kazal-like domain-containing protein.
      
 0.533
CG34015
GEO11148p1; Catalytic activity.
      
 0.532
CG7339
GM16372p; DNA-directed 5'-3' RNA polymerase activity. It is involved in the biological process described with: transcription initiation from RNA polymerase III promoter.
      
 0.530
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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