node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
D | SoxN | FBpp0075488 | FBpp0303243 | Dichaete (D) encodes an HMG-domain protein and member of the Sox family of transcription factors. Its roles include hindgut development, embryonic segmentation, and nervous system development. | SoxNeuro, isoform B; SoxNeuro (SoxN) encodes an HMG-domain transcription factor. In early embryos it specifies neural progenitors in the central nervous system, while in later embryos it negatively regulates Wg signaling and controls expression of genes required for denticle construction with the product of ovo. | 0.801 |
D | nub | FBpp0075488 | FBpp0111554 | Dichaete (D) encodes an HMG-domain protein and member of the Sox family of transcription factors. Its roles include hindgut development, embryonic segmentation, and nervous system development. | Protein nubbin; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. Repressed directly or indirectly by the BX-C homeotic proteins. Belongs to the POU transcription factor family. Class-2 subfamily. | 0.701 |
D | pdm2 | FBpp0075488 | FBpp0309439 | Dichaete (D) encodes an HMG-domain protein and member of the Sox family of transcription factors. Its roles include hindgut development, embryonic segmentation, and nervous system development. | POU domain protein 2, isoform B; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. May act as an octamer-dependent activator of transcription. Could also play an early role in specific ectodermal cells, and a subsequent role in the embryonic nervous system. | 0.743 |
SoxN | D | FBpp0303243 | FBpp0075488 | SoxNeuro, isoform B; SoxNeuro (SoxN) encodes an HMG-domain transcription factor. In early embryos it specifies neural progenitors in the central nervous system, while in later embryos it negatively regulates Wg signaling and controls expression of genes required for denticle construction with the product of ovo. | Dichaete (D) encodes an HMG-domain protein and member of the Sox family of transcription factors. Its roles include hindgut development, embryonic segmentation, and nervous system development. | 0.801 |
SoxN | nub | FBpp0303243 | FBpp0111554 | SoxNeuro, isoform B; SoxNeuro (SoxN) encodes an HMG-domain transcription factor. In early embryos it specifies neural progenitors in the central nervous system, while in later embryos it negatively regulates Wg signaling and controls expression of genes required for denticle construction with the product of ovo. | Protein nubbin; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. Repressed directly or indirectly by the BX-C homeotic proteins. Belongs to the POU transcription factor family. Class-2 subfamily. | 0.532 |
SoxN | pdm2 | FBpp0303243 | FBpp0309439 | SoxNeuro, isoform B; SoxNeuro (SoxN) encodes an HMG-domain transcription factor. In early embryos it specifies neural progenitors in the central nervous system, while in later embryos it negatively regulates Wg signaling and controls expression of genes required for denticle construction with the product of ovo. | POU domain protein 2, isoform B; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. May act as an octamer-dependent activator of transcription. Could also play an early role in specific ectodermal cells, and a subsequent role in the embryonic nervous system. | 0.644 |
btd | hb | FBpp0071314 | FBpp0081432 | Transcription factor btd; Buttonhead (btd) encodes a triple C(2)H(2) zinc finger protein structurally and functionally related to the human transcription factors Sp5, Sp8, and Sp9. The product of btd contributes to embryonic head segmentation, leg development, embryonic hematopoiesis, PNS formation, and maintenance of the functional heterogeneity of brain neural stem cells. | Protein hunchback; Gap class segmentation protein that controls development of head structures; Belongs to the hunchback C2H2-type zinc-finger protein family. | 0.631 |
btd | nub | FBpp0071314 | FBpp0111554 | Transcription factor btd; Buttonhead (btd) encodes a triple C(2)H(2) zinc finger protein structurally and functionally related to the human transcription factors Sp5, Sp8, and Sp9. The product of btd contributes to embryonic head segmentation, leg development, embryonic hematopoiesis, PNS formation, and maintenance of the functional heterogeneity of brain neural stem cells. | Protein nubbin; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. Repressed directly or indirectly by the BX-C homeotic proteins. Belongs to the POU transcription factor family. Class-2 subfamily. | 0.731 |
btd | pdm2 | FBpp0071314 | FBpp0309439 | Transcription factor btd; Buttonhead (btd) encodes a triple C(2)H(2) zinc finger protein structurally and functionally related to the human transcription factors Sp5, Sp8, and Sp9. The product of btd contributes to embryonic head segmentation, leg development, embryonic hematopoiesis, PNS formation, and maintenance of the functional heterogeneity of brain neural stem cells. | POU domain protein 2, isoform B; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. May act as an octamer-dependent activator of transcription. Could also play an early role in specific ectodermal cells, and a subsequent role in the embryonic nervous system. | 0.710 |
grh | hb | FBpp0288984 | FBpp0081432 | Protein grainyhead; Grainy head (grh) encodes the founding member of a highly conserved family of transcription factors essential for embryonic development. It is both a transcriptional activator and repressor, responsible for the proper expression of many genes primarily involved in epithelial cell fate, barrier formation, wound healing, tube morphogenesis and proliferation of larval neuroblasts; Belongs to the grh/CP2 family. Grainyhead subfamily. | Protein hunchback; Gap class segmentation protein that controls development of head structures; Belongs to the hunchback C2H2-type zinc-finger protein family. | 0.633 |
grh | kek2 | FBpp0288984 | FBpp0079836 | Protein grainyhead; Grainy head (grh) encodes the founding member of a highly conserved family of transcription factors essential for embryonic development. It is both a transcriptional activator and repressor, responsible for the proper expression of many genes primarily involved in epithelial cell fate, barrier formation, wound healing, tube morphogenesis and proliferation of larval neuroblasts; Belongs to the grh/CP2 family. Grainyhead subfamily. | Kekkon 2. | 0.401 |
grh | nub | FBpp0288984 | FBpp0111554 | Protein grainyhead; Grainy head (grh) encodes the founding member of a highly conserved family of transcription factors essential for embryonic development. It is both a transcriptional activator and repressor, responsible for the proper expression of many genes primarily involved in epithelial cell fate, barrier formation, wound healing, tube morphogenesis and proliferation of larval neuroblasts; Belongs to the grh/CP2 family. Grainyhead subfamily. | Protein nubbin; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. Repressed directly or indirectly by the BX-C homeotic proteins. Belongs to the POU transcription factor family. Class-2 subfamily. | 0.481 |
grh | pdm2 | FBpp0288984 | FBpp0309439 | Protein grainyhead; Grainy head (grh) encodes the founding member of a highly conserved family of transcription factors essential for embryonic development. It is both a transcriptional activator and repressor, responsible for the proper expression of many genes primarily involved in epithelial cell fate, barrier formation, wound healing, tube morphogenesis and proliferation of larval neuroblasts; Belongs to the grh/CP2 family. Grainyhead subfamily. | POU domain protein 2, isoform B; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. May act as an octamer-dependent activator of transcription. Could also play an early role in specific ectodermal cells, and a subsequent role in the embryonic nervous system. | 0.645 |
grh | sqz | FBpp0288984 | FBpp0083147 | Protein grainyhead; Grainy head (grh) encodes the founding member of a highly conserved family of transcription factors essential for embryonic development. It is both a transcriptional activator and repressor, responsible for the proper expression of many genes primarily involved in epithelial cell fate, barrier formation, wound healing, tube morphogenesis and proliferation of larval neuroblasts; Belongs to the grh/CP2 family. Grainyhead subfamily. | Zinc finger protein squeeze; Transcription factor involved in neuronal fate specification. First required in embryonic CNS development to define the number of cells that express apterous (ap) in the ap thoracic cluster of interneurons. Later on, it plays a central role in the combinatorial code of transcription factors that specifies the fate of the Tv neuron in the ap cluster by participating in the transcription regulation of FMRFa in Tv cells. Also required for projection neuron dendritic targeting. | 0.612 |
grh | svp | FBpp0288984 | FBpp0082035 | Protein grainyhead; Grainy head (grh) encodes the founding member of a highly conserved family of transcription factors essential for embryonic development. It is both a transcriptional activator and repressor, responsible for the proper expression of many genes primarily involved in epithelial cell fate, barrier formation, wound healing, tube morphogenesis and proliferation of larval neuroblasts; Belongs to the grh/CP2 family. Grainyhead subfamily. | Steroid receptor seven-up, isoform A; Receptor that is required in photoreceptors R1, R3, R4 and R6 during eye development; generation of the ganglion mother cell-2 (GMC- 2) fate in the nb7-3 lineage, coinciding with the transition in the expression of HB to KR in the neuroblasts (NBs). Belongs to the nuclear hormone receptor family. NR2 subfamily. | 0.617 |
hb | btd | FBpp0081432 | FBpp0071314 | Protein hunchback; Gap class segmentation protein that controls development of head structures; Belongs to the hunchback C2H2-type zinc-finger protein family. | Transcription factor btd; Buttonhead (btd) encodes a triple C(2)H(2) zinc finger protein structurally and functionally related to the human transcription factors Sp5, Sp8, and Sp9. The product of btd contributes to embryonic head segmentation, leg development, embryonic hematopoiesis, PNS formation, and maintenance of the functional heterogeneity of brain neural stem cells. | 0.631 |
hb | grh | FBpp0081432 | FBpp0288984 | Protein hunchback; Gap class segmentation protein that controls development of head structures; Belongs to the hunchback C2H2-type zinc-finger protein family. | Protein grainyhead; Grainy head (grh) encodes the founding member of a highly conserved family of transcription factors essential for embryonic development. It is both a transcriptional activator and repressor, responsible for the proper expression of many genes primarily involved in epithelial cell fate, barrier formation, wound healing, tube morphogenesis and proliferation of larval neuroblasts; Belongs to the grh/CP2 family. Grainyhead subfamily. | 0.633 |
hb | kek2 | FBpp0081432 | FBpp0079836 | Protein hunchback; Gap class segmentation protein that controls development of head structures; Belongs to the hunchback C2H2-type zinc-finger protein family. | Kekkon 2. | 0.802 |
hb | nub | FBpp0081432 | FBpp0111554 | Protein hunchback; Gap class segmentation protein that controls development of head structures; Belongs to the hunchback C2H2-type zinc-finger protein family. | Protein nubbin; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. Repressed directly or indirectly by the BX-C homeotic proteins. Belongs to the POU transcription factor family. Class-2 subfamily. | 0.672 |
hb | pdm2 | FBpp0081432 | FBpp0309439 | Protein hunchback; Gap class segmentation protein that controls development of head structures; Belongs to the hunchback C2H2-type zinc-finger protein family. | POU domain protein 2, isoform B; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. May act as an octamer-dependent activator of transcription. Could also play an early role in specific ectodermal cells, and a subsequent role in the embryonic nervous system. | 0.870 |