STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG5867BcDNA.GH05536. (262 aa)    
Predicted Functional Partners:
CG14661
Uncharacterized protein, isoform A.
   
  
0.679
nAChRalpha2
Acetylcholine receptor subunit alpha-like 2; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
      
 0.554
CG13155
Uncharacterized protein.
   
  
 0.502
CG33060
Uncharacterized protein; It is involved in the biological process described with: histone H3-K4 methylation.
      
 0.491
rg
Neurobeachin; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins. Required for correct retinal pattern formation and may function in cell fate determination through its interactions with the EGFR and Notch signaling pathways. Required for associative odor learning and short-term memory. Involved in development of the neuromuscular junction and the mushroom body. Belongs to the WD repeat neurobeachin family.
      
 0.491
Ptpmeg
Protein tyrosine phosphatase Meg (Ptpmeg) encodes a tyrosine phosphatase that interacts with the product of Eps-15. It negatively regulates border cell migration during oogenesis. It also inhibits the EGFR/Ras/mitogen-activated protein kinase signaling pathway during wing morphogenesis; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.
      
 0.465
Obp56e
Odorant-binding protein 56e, isoform A; Odorant binding. It is involved in the biological process described with: sensory perception of chemical stimulus; sensory perception of smell; multicellular organism reproduction.
   
  
 0.457
dpr10
Defective proboscis extension response 10, isoform A; It is involved in the biological process described with: sensory perception of chemical stimulus; synapse organization.
      
 0.439
bol
Protein boule; RNA-binding protein that plays a central role in spermatogenesis. Required for meiotic entry and germline differentiation, at the transition between G2 and M phases of meiosis I. Acts by regulating translation of specific mRNAs, possibly by binding to their 3'-UTR. Essential for translation of twine (twe) mRNA. Required for the expression of various genes such as CG6784, CG17210, CG15841 scpr-B, scpr-C, and rho-6; Belongs to the RRM DAZ family.
      
 0.430
CG6414
Carboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family.
      
 0.426
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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