node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCT1 | CCT8 | FBpp0083684 | FBpp0087764 | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | Chaperonin containing TCP1 subunit 8; Unfolded protein binding; ATP binding. It is involved in the biological process described with: protein folding. | 0.999 |
CCT1 | CG11267 | FBpp0083684 | FBpp0075609 | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | RH34413p; Metal ion binding; unfolded protein binding; chaperone binding. It is involved in the biological process described with: chaperone cofactor-dependent protein refolding; Belongs to the GroES chaperonin family. | 0.838 |
CCT1 | CG9920 | FBpp0083684 | FBpp0082377 | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | AT30951p; Chaperone binding; unfolded protein binding; metal ion binding. It is involved in the biological process described with: chaperone cofactor-dependent protein refolding; Belongs to the GroES chaperonin family. | 0.780 |
CCT1 | Gp93 | FBpp0083684 | FBpp0084623 | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | 0.742 |
CCT1 | Hsc70-5 | FBpp0083684 | FBpp0086694 | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | Heat shock 70 kDa protein cognate 5. | 0.769 |
CCT1 | Hsp60D | FBpp0083684 | FBpp0080096 | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | Heat shock protein 60D (Hsp60D) encodes a protein involved in caspase-mediated apoptosis and polyQ-mediated neurodegeneration; Belongs to the chaperonin (HSP60) family. | 0.722 |
CCT1 | Hsp70Bc | FBpp0083684 | FBpp0082107 | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | Heat-shock-protein-70Bc (Hsp70Bc) encodes a protein involved in response to heat shock, hypoxia and drugs. | 0.500 |
CCT1 | Hsp83 | FBpp0083684 | FBpp0305095 | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Together with Hop and piwi, mediates canalization, also known as develop [...] | 0.886 |
CCT1 | Lon | FBpp0083684 | FBpp0271918 | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner. Regulates mitochondrial DNA (mtDNA) copy number and transcription by [...] | 0.609 |
CCT1 | Roe1 | FBpp0083684 | FBpp0086795 | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity). | 0.768 |
CCT8 | CCT1 | FBpp0087764 | FBpp0083684 | Chaperonin containing TCP1 subunit 8; Unfolded protein binding; ATP binding. It is involved in the biological process described with: protein folding. | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | 0.999 |
CCT8 | CG11267 | FBpp0087764 | FBpp0075609 | Chaperonin containing TCP1 subunit 8; Unfolded protein binding; ATP binding. It is involved in the biological process described with: protein folding. | RH34413p; Metal ion binding; unfolded protein binding; chaperone binding. It is involved in the biological process described with: chaperone cofactor-dependent protein refolding; Belongs to the GroES chaperonin family. | 0.716 |
CCT8 | CG9920 | FBpp0087764 | FBpp0082377 | Chaperonin containing TCP1 subunit 8; Unfolded protein binding; ATP binding. It is involved in the biological process described with: protein folding. | AT30951p; Chaperone binding; unfolded protein binding; metal ion binding. It is involved in the biological process described with: chaperone cofactor-dependent protein refolding; Belongs to the GroES chaperonin family. | 0.659 |
CCT8 | Gp93 | FBpp0087764 | FBpp0084623 | Chaperonin containing TCP1 subunit 8; Unfolded protein binding; ATP binding. It is involved in the biological process described with: protein folding. | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | 0.655 |
CCT8 | Hsc70-5 | FBpp0087764 | FBpp0086694 | Chaperonin containing TCP1 subunit 8; Unfolded protein binding; ATP binding. It is involved in the biological process described with: protein folding. | Heat shock 70 kDa protein cognate 5. | 0.544 |
CCT8 | Hsp60D | FBpp0087764 | FBpp0080096 | Chaperonin containing TCP1 subunit 8; Unfolded protein binding; ATP binding. It is involved in the biological process described with: protein folding. | Heat shock protein 60D (Hsp60D) encodes a protein involved in caspase-mediated apoptosis and polyQ-mediated neurodegeneration; Belongs to the chaperonin (HSP60) family. | 0.830 |
CCT8 | Hsp83 | FBpp0087764 | FBpp0305095 | Chaperonin containing TCP1 subunit 8; Unfolded protein binding; ATP binding. It is involved in the biological process described with: protein folding. | Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Together with Hop and piwi, mediates canalization, also known as develop [...] | 0.867 |
CG11267 | CCT1 | FBpp0075609 | FBpp0083684 | RH34413p; Metal ion binding; unfolded protein binding; chaperone binding. It is involved in the biological process described with: chaperone cofactor-dependent protein refolding; Belongs to the GroES chaperonin family. | T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | 0.838 |
CG11267 | CCT8 | FBpp0075609 | FBpp0087764 | RH34413p; Metal ion binding; unfolded protein binding; chaperone binding. It is involved in the biological process described with: chaperone cofactor-dependent protein refolding; Belongs to the GroES chaperonin family. | Chaperonin containing TCP1 subunit 8; Unfolded protein binding; ATP binding. It is involved in the biological process described with: protein folding. | 0.716 |
CG11267 | Gp93 | FBpp0075609 | FBpp0084623 | RH34413p; Metal ion binding; unfolded protein binding; chaperone binding. It is involved in the biological process described with: chaperone cofactor-dependent protein refolding; Belongs to the GroES chaperonin family. | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | 0.955 |