STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CAH1Carbonic anhydrase 1 (CAH1) encodes an alpha-class carbonate dehydratase that catalyzes the reversible hydration/dehydration of carbon dioxide to bicarbonate and protons. (270 aa)    
Predicted Functional Partners:
CG4716
GH06388p; Methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity.
   
  
 0.840
CG6287
GH03305p; NAD binding; phosphoglycerate dehydrogenase activity. It is involved in the biological process described with: cellular amino acid metabolic process; oxidation-reduction process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
  
 0.838
S-Lap4
Sperm-Leucylaminopeptidase 4; Metalloexopeptidase activity; aminopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis.
      
 0.837
CAH7
Carbonic anhydrase 7, isoform A; Zinc ion binding; hydro-lyase activity; carbonate dehydratase activity. It is involved in the biological process described with: one-carbon metabolic process; Belongs to the alpha-carbonic anhydrase family.
  
 
 
0.829
Sh3beta
SH3 domain-binding glutamic acid-rich protein homolog.
      
 0.654
CAH2
Carbonic anhydrase 2 (CAH2) encodes an alpha-class carbonate dehydratase that catalyzes the reversible hydration/dehydration of carbon dioxide to bicarbonate and protons.
  
 
0.653
CAHbeta
Carbonic anhydrase beta (CAHbeta) encodes a beta-class carbonate dehydratase that catalyzes the reversible hydration/dehydration of carbon dioxide to bicarbonate and protons.
      
 0.649
Vha100-5
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
  
 0.643
Non3
Ribosome production factor 2 homolog; Required for normal assembly of the mitotic spindle. May be involved in both centrosome-dependent and centrosome-independent spindle assembly programs; Belongs to the RPF2 family.
   
 
 0.636
Vha100-2
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
  
 0.620
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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