STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG15269Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific. It is involved in the biological process described with: regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II. (587 aa)    
Predicted Functional Partners:
CG4168
Uncharacterized protein, isoform B.
    
 
 0.918
CG13070
Uncharacterized protein.
   
    0.559
bon
Bonus, isoform C; Bonus (bon) encodes a nuclear receptor cofactor involved in axon guidance and chromatin organization.
   
 0.537
dwg
Deformed wings (dwg) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in regulatory regions (predominantly promoters). dwg product binding site was found in the insulator encoded by scs, and its functions include enhancer blocking, support of distant interactions and recruitment of transcription factors.
  
  
 
0.499
jim
Jim, isoform F; Jim (jim) encodes a zinc finger C2H2 transcription factor involved in dendrite morphogenesis and regulation of chromatin silencing.
  
  
 
0.494
CG18735
MIP24941p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
    0.487
CG13023
Uncharacterized protein, isoform A.
   
    0.477
CG3847
LD24968p; RNA polymerase II regulatory region sequence-specific DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
  
  
 
0.445
CG13081
Uncharacterized protein, isoform A.
   
   0.440
fzo
Transmembrane GTPase fzo; Essential transmembrane GTPase, which mediates mitochondrial fusion during spermatogenesis. In early spermatocytes, fusion of mitochondria give rise to two organelles named Nebenkern and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. Essential for fertility.
    
 
 0.405
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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