node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acam | Cam | FBpp0291175 | FBpp0293502 | Calmodulin-related protein 97A; May be involved in calcium-mediated signal transduction. | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+) (By similarity). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). In photoreceptor cells, light-induced Ca(2+) influx activates calmodulin, which in turn is likely to promote Crag activity in trafficking of newly synthesized ninaE (Rh1) from the trans-Golgi network to rhabdomere membranes. Together with Akap200, regulates PKA activity and ethanol-induced sensitivity and tolerance. | 0.950 |
Acam | Mlc-c | FBpp0291175 | FBpp0300803 | Calmodulin-related protein 97A; May be involved in calcium-mediated signal transduction. | Myosin light chain cytoplasmic (Mlc-c) encodes a subunit of the myosin complex that is involved in actin filament-based movement. | 0.743 |
Acam | ck | FBpp0291175 | FBpp0310275 | Calmodulin-related protein 97A; May be involved in calcium-mediated signal transduction. | Myosin-VIIa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements: can function in cells as a single-molecule cargo transporter. A very slow and high-duty-ratio motor, may be suitable for tension maintenance of actin filaments. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a key role in the formation of cellular projections and other actin-based functions required for embryonic and larval viability. Necessary for auditory transduction: [...] | 0.840 |
Acam | didum | FBpp0291175 | FBpp0088684 | Calmodulin-related protein 97A; May be involved in calcium-mediated signal transduction. | Dilute class unconventional myosin (didum) encodes a class V unconventional myosin that binds actin and hydrolyzes ATP. It functions in mRNA localization in the oocyte, spermatid individualization during spermatogenesis, transport of pigment granules in photoreceptors and mitochondrial transport in neuronal cells; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.906 |
Acam | jar | FBpp0291175 | FBpp0290582 | Calmodulin-related protein 97A; May be involved in calcium-mediated signal transduction. | Myosin heavy chain 95F; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Together CLIP-190 and jar may coordinate the interaction between the actin and microtubule cytoskeleton. May link endocytic vesicles to microtubules and may be involved in transport in the early embryo and in the dynamic process of dorsal closure. It is believed that its function changes during the life cycle. | 0.975 |
CG5921 | Cad99C | FBpp0293886 | FBpp0084854 | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | 0.967 |
CG5921 | Cib2 | FBpp0293886 | FBpp0293260 | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | Calcium and integrin binding family member 2; Calcium ion binding; calcium-dependent protein serine/threonine phosphatase activity. It is involved in the biological process described with: calcium ion homeostasis; phototransduction. | 0.673 |
CG5921 | Sans | FBpp0293886 | FBpp0086903 | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | Scaffold protein containing ankyrin repeats and SAM domain (Sans) encodes a putative scaffolding protein containing three ankyrin repeats and a sterile alpha motif domain. | 0.965 |
CG5921 | ck | FBpp0293886 | FBpp0310275 | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | Myosin-VIIa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements: can function in cells as a single-molecule cargo transporter. A very slow and high-duty-ratio motor, may be suitable for tension maintenance of actin filaments. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a key role in the formation of cellular projections and other actin-based functions required for embryonic and larval viability. Necessary for auditory transduction: [...] | 0.986 |
CG5921 | dysc | FBpp0293886 | FBpp0303444 | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | Dyschronic, isoform G; Dyschronic (dysc) encodes a protein that regulates the localization of the calcium-activated potassium channel encoded by slo. The product of dysc impacts circadian locomotor patterns, synaptic morphology, active zone structure, and both spontaneous and evoked neurotransmitter release. | 0.910 |
Cad99C | CG5921 | FBpp0084854 | FBpp0293886 | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | 0.967 |
Cad99C | Cib2 | FBpp0084854 | FBpp0293260 | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | Calcium and integrin binding family member 2; Calcium ion binding; calcium-dependent protein serine/threonine phosphatase activity. It is involved in the biological process described with: calcium ion homeostasis; phototransduction. | 0.605 |
Cad99C | Sans | FBpp0084854 | FBpp0086903 | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | Scaffold protein containing ankyrin repeats and SAM domain (Sans) encodes a putative scaffolding protein containing three ankyrin repeats and a sterile alpha motif domain. | 0.629 |
Cad99C | ck | FBpp0084854 | FBpp0310275 | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | Myosin-VIIa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements: can function in cells as a single-molecule cargo transporter. A very slow and high-duty-ratio motor, may be suitable for tension maintenance of actin filaments. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a key role in the formation of cellular projections and other actin-based functions required for embryonic and larval viability. Necessary for auditory transduction: [...] | 0.980 |
Cad99C | dysc | FBpp0084854 | FBpp0303444 | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | Dyschronic, isoform G; Dyschronic (dysc) encodes a protein that regulates the localization of the calcium-activated potassium channel encoded by slo. The product of dysc impacts circadian locomotor patterns, synaptic morphology, active zone structure, and both spontaneous and evoked neurotransmitter release. | 0.900 |
Cam | Acam | FBpp0293502 | FBpp0291175 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+) (By similarity). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). In photoreceptor cells, light-induced Ca(2+) influx activates calmodulin, which in turn is likely to promote Crag activity in trafficking of newly synthesized ninaE (Rh1) from the trans-Golgi network to rhabdomere membranes. Together with Akap200, regulates PKA activity and ethanol-induced sensitivity and tolerance. | Calmodulin-related protein 97A; May be involved in calcium-mediated signal transduction. | 0.950 |
Cam | Mlc-c | FBpp0293502 | FBpp0300803 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+) (By similarity). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). In photoreceptor cells, light-induced Ca(2+) influx activates calmodulin, which in turn is likely to promote Crag activity in trafficking of newly synthesized ninaE (Rh1) from the trans-Golgi network to rhabdomere membranes. Together with Akap200, regulates PKA activity and ethanol-induced sensitivity and tolerance. | Myosin light chain cytoplasmic (Mlc-c) encodes a subunit of the myosin complex that is involved in actin filament-based movement. | 0.744 |
Cam | ck | FBpp0293502 | FBpp0310275 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+) (By similarity). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). In photoreceptor cells, light-induced Ca(2+) influx activates calmodulin, which in turn is likely to promote Crag activity in trafficking of newly synthesized ninaE (Rh1) from the trans-Golgi network to rhabdomere membranes. Together with Akap200, regulates PKA activity and ethanol-induced sensitivity and tolerance. | Myosin-VIIa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements: can function in cells as a single-molecule cargo transporter. A very slow and high-duty-ratio motor, may be suitable for tension maintenance of actin filaments. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a key role in the formation of cellular projections and other actin-based functions required for embryonic and larval viability. Necessary for auditory transduction: [...] | 0.957 |
Cam | didum | FBpp0293502 | FBpp0088684 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+) (By similarity). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). In photoreceptor cells, light-induced Ca(2+) influx activates calmodulin, which in turn is likely to promote Crag activity in trafficking of newly synthesized ninaE (Rh1) from the trans-Golgi network to rhabdomere membranes. Together with Akap200, regulates PKA activity and ethanol-induced sensitivity and tolerance. | Dilute class unconventional myosin (didum) encodes a class V unconventional myosin that binds actin and hydrolyzes ATP. It functions in mRNA localization in the oocyte, spermatid individualization during spermatogenesis, transport of pigment granules in photoreceptors and mitochondrial transport in neuronal cells; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.951 |
Cam | jar | FBpp0293502 | FBpp0290582 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+) (By similarity). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). In photoreceptor cells, light-induced Ca(2+) influx activates calmodulin, which in turn is likely to promote Crag activity in trafficking of newly synthesized ninaE (Rh1) from the trans-Golgi network to rhabdomere membranes. Together with Akap200, regulates PKA activity and ethanol-induced sensitivity and tolerance. | Myosin heavy chain 95F; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Together CLIP-190 and jar may coordinate the interaction between the actin and microtubule cytoskeleton. May link endocytic vesicles to microtubules and may be involved in transport in the early embryo and in the dynamic process of dorsal closure. It is believed that its function changes during the life cycle. | 0.932 |