STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG10428Glutathione S-transferase C-terminal domain-containing protein homolog; Belongs to the GSTCD family. (585 aa)    
Predicted Functional Partners:
trio
Trio, isoform A; Trio (trio) encodes a Rho guanine nucleotide exchange factor (GEF) that activates the Rho-family GTPases to regulate actin structure and cell adhesion. The GEF encoded by trio acts in several signaling pathways, including Abl tyrosine kinase and BMP signaling pathways. The product of trio is involved in neural wiring (axon and dendrite patterning and synaptogenesis) and muscle development.
      
 0.668
ry
Xanthine dehydrogenase; Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid (By similarity).
    
 
 0.633
mRpS28
Mitochondrial ribosomal protein S28; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation.
   
  
 0.609
AOX4
Aldehyde oxidase 4 (AOX4) encodes an oxidoreductase that catalyzes the oxidation of pyridoxal to pyridoxate with the release of hydrogen peroxide.
    
 
 0.605
CG12975
Multifunctional methyltransferase subunit TRM112-like protein; Acts as an activator of both RNA and protein methyltransferases.
   
 
 0.549
AOX2
Aldehyde oxidase 2 (AOX2) encodes a pyridoxal oxidase involved in pyridoxal metabolism.
    
 
 0.538
AOX3
Aldehyde oxidase 3 (AOX3) encodes a pyridoxal oxidase involved in pyridoxal metabolism.
    
 
 0.535
JTBR
DJTB-like protein; It is involved in the biological process described with: mitotic cytokinesis.
 
 
    0.458
AOX1
Aldehyde oxidase 1 (AOX1) encodes a pyridoxal oxidase involved in pyridoxal metabolism.
    
 
 0.433
CG9723
LD39612p.
      
 0.407
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.