node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AdSS | Argl | FBpp0083395 | FBpp0289058 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Argininosuccinate lyase activity. It is involved in the biological process described with: arginine biosynthetic process via ornithine. | 0.726 |
AdSS | AsnS | FBpp0083395 | FBpp0089009 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Asparagine synthase (glutamine-hydrolyzing) activity. It is involved in the biological process described with: asparagine biosynthetic process. | 0.951 |
AdSS | Ass | FBpp0083395 | FBpp0307951 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | ATP binding; argininosuccinate synthase activity. It is involved in the biological process described with: arginine biosynthetic process; argininosuccinate metabolic process; urea cycle; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.970 |
AdSS | CG7860 | FBpp0083395 | FBpp0073861 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Probable isoaspartyl peptidase/L-asparaginase CG7860 alpha chain; Has both L-asparaginase and beta-aspartyl peptidase activity. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. | 0.910 |
AdSS | Got1 | FBpp0083395 | FBpp0086370 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Glutamate oxaloacetate transaminase 1 (Got1) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis. | 0.960 |
AdSS | Got2 | FBpp0083395 | FBpp0077537 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Aspartate aminotransferase; Glutamate oxaloacetate transaminase 2 (Got2) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis, which in turn regulates postsynaptic receptor field size. | 0.953 |
AdSS | Oat | FBpp0083395 | FBpp0074729 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Ornithine aminotransferase, mitochondrial; Ornithine-oxo-acid transaminase activity; identical protein binding; pyridoxal phosphate binding. It is involved in the biological process described with: arginine catabolic process to proline via ornithine; ornithine metabolic process; arginine catabolic process to glutamate. | 0.596 |
AdSS | r | FBpp0083395 | FBpp0088675 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Glutamine-dependent carbamoyl-phosphate synthase; Rudimentary (r) encodes the CAD protein that catalyzes the initial steps of de novo pyrimidine biosynthesis. r depletion results in wing malformations and pyrimidine auxotrophy. | 0.985 |
AdSS | t | FBpp0083395 | FBpp0071270 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | Tan, isoform A; Tan (t) encodes a hydrolase involved in both the conversion of N-beta-alanyldopamine to dopamine in the cuticle and central nervous system, and the conversion of beta-alanylhistamine (carcinine) to histamine in the retina. It functions in vision, cuticular melanization, and neurotransmitter recycling. | 0.596 |
Argl | AdSS | FBpp0289058 | FBpp0083395 | Argininosuccinate lyase activity. It is involved in the biological process described with: arginine biosynthetic process via ornithine. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | 0.726 |
Argl | AsnS | FBpp0289058 | FBpp0089009 | Argininosuccinate lyase activity. It is involved in the biological process described with: arginine biosynthetic process via ornithine. | Asparagine synthase (glutamine-hydrolyzing) activity. It is involved in the biological process described with: asparagine biosynthetic process. | 0.461 |
Argl | Ass | FBpp0289058 | FBpp0307951 | Argininosuccinate lyase activity. It is involved in the biological process described with: arginine biosynthetic process via ornithine. | ATP binding; argininosuccinate synthase activity. It is involved in the biological process described with: arginine biosynthetic process; argininosuccinate metabolic process; urea cycle; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.999 |
Argl | Nos | FBpp0289058 | FBpp0079777 | Argininosuccinate lyase activity. It is involved in the biological process described with: arginine biosynthetic process via ornithine. | Nitric oxide synthase; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. Truncated isoforms (isoform 3- isoform 6) are able to form intracellular complexes with the full- length protein and serve as dominant negative inhibitors of the enzyme activity; Belongs to the NOS family. | 0.953 |
Argl | Oat | FBpp0289058 | FBpp0074729 | Argininosuccinate lyase activity. It is involved in the biological process described with: arginine biosynthetic process via ornithine. | Ornithine aminotransferase, mitochondrial; Ornithine-oxo-acid transaminase activity; identical protein binding; pyridoxal phosphate binding. It is involved in the biological process described with: arginine catabolic process to proline via ornithine; ornithine metabolic process; arginine catabolic process to glutamate. | 0.948 |
Argl | r | FBpp0289058 | FBpp0088675 | Argininosuccinate lyase activity. It is involved in the biological process described with: arginine biosynthetic process via ornithine. | Glutamine-dependent carbamoyl-phosphate synthase; Rudimentary (r) encodes the CAD protein that catalyzes the initial steps of de novo pyrimidine biosynthesis. r depletion results in wing malformations and pyrimidine auxotrophy. | 0.932 |
Argl | t | FBpp0289058 | FBpp0071270 | Argininosuccinate lyase activity. It is involved in the biological process described with: arginine biosynthetic process via ornithine. | Tan, isoform A; Tan (t) encodes a hydrolase involved in both the conversion of N-beta-alanyldopamine to dopamine in the cuticle and central nervous system, and the conversion of beta-alanylhistamine (carcinine) to histamine in the retina. It functions in vision, cuticular melanization, and neurotransmitter recycling. | 0.936 |
AsnS | AdSS | FBpp0089009 | FBpp0083395 | Asparagine synthase (glutamine-hydrolyzing) activity. It is involved in the biological process described with: asparagine biosynthetic process. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Plays a role in the regulation of adult life span. | 0.951 |
AsnS | Argl | FBpp0089009 | FBpp0289058 | Asparagine synthase (glutamine-hydrolyzing) activity. It is involved in the biological process described with: asparagine biosynthetic process. | Argininosuccinate lyase activity. It is involved in the biological process described with: arginine biosynthetic process via ornithine. | 0.461 |
AsnS | Ass | FBpp0089009 | FBpp0307951 | Asparagine synthase (glutamine-hydrolyzing) activity. It is involved in the biological process described with: asparagine biosynthetic process. | ATP binding; argininosuccinate synthase activity. It is involved in the biological process described with: arginine biosynthetic process; argininosuccinate metabolic process; urea cycle; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.962 |
AsnS | CG7860 | FBpp0089009 | FBpp0073861 | Asparagine synthase (glutamine-hydrolyzing) activity. It is involved in the biological process described with: asparagine biosynthetic process. | Probable isoaspartyl peptidase/L-asparaginase CG7860 alpha chain; Has both L-asparaginase and beta-aspartyl peptidase activity. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. | 0.933 |