node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG32568 | CG4733 | FBpp0310019 | FBpp0300986 | Uncharacterized protein, isoform B; Protein phosphatase activator activity. It is involved in the biological process described with: regulation of protein autophosphorylation; signal transduction; protein dephosphorylation. | MIP22305p; CG4733 encodes a protein that is predicted to be the B"/PR72 subunit of Protein Phosphatase 2A (PP2A) regulatory B unit. The B subunits determine the substrate specificity of the enzyme. | 0.935 |
CG32568 | Pp2A-29B | FBpp0310019 | FBpp0308836 | Uncharacterized protein, isoform B; Protein phosphatase activator activity. It is involved in the biological process described with: regulation of protein autophosphorylation; signal transduction; protein dephosphorylation. | Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. | 0.989 |
CG32568 | mts | FBpp0310019 | FBpp0310062 | Uncharacterized protein, isoform B; Protein phosphatase activator activity. It is involved in the biological process described with: regulation of protein autophosphorylation; signal transduction; protein dephosphorylation. | Serine/threonine-protein phosphatase PP2A; Microtubule star (mts) encodes the catalytic subunit of protein phosphatase 2A. It is involved in various developmental processes and signaling pathways, such as Hh signaling and Wingless signaling; Belongs to the PPP phosphatase family. PP-2A subfamily. | 0.989 |
CG32568 | tws | FBpp0310019 | FBpp0311386 | Uncharacterized protein, isoform B; Protein phosphatase activator activity. It is involved in the biological process described with: regulation of protein autophosphorylation; signal transduction; protein dephosphorylation. | Protein phosphatase PP2A 55 kDa regulatory subunit; Could perform a substrate recognition function or could be responsible for targeting the enzyme complex to the appropriate subcellular compartment. | 0.966 |
CG32568 | wdb | FBpp0310019 | FBpp0084575 | Uncharacterized protein, isoform B; Protein phosphatase activator activity. It is involved in the biological process described with: regulation of protein autophosphorylation; signal transduction; protein dephosphorylation. | Widerborst (wdb) encodes a B' regulatory subunit of the serine/threonine phosphatase complex PP2A. It regulates Hedgehog, protein kinase B and insulin receptor signaling pathways. | 0.911 |
CG32568 | wrd | FBpp0310019 | FBpp0082978 | Uncharacterized protein, isoform B; Protein phosphatase activator activity. It is involved in the biological process described with: regulation of protein autophosphorylation; signal transduction; protein dephosphorylation. | Well-rounded, isoform B; Well-rounded (wrd) encodes one of the two regulatory B' subunits of the protein phosphatase PP2A. It influences metabolism and growth via negative regulation of the InR/TOR signalling network. | 0.816 |
CG4733 | CG32568 | FBpp0300986 | FBpp0310019 | MIP22305p; CG4733 encodes a protein that is predicted to be the B"/PR72 subunit of Protein Phosphatase 2A (PP2A) regulatory B unit. The B subunits determine the substrate specificity of the enzyme. | Uncharacterized protein, isoform B; Protein phosphatase activator activity. It is involved in the biological process described with: regulation of protein autophosphorylation; signal transduction; protein dephosphorylation. | 0.935 |
CG4733 | Pp2A-29B | FBpp0300986 | FBpp0308836 | MIP22305p; CG4733 encodes a protein that is predicted to be the B"/PR72 subunit of Protein Phosphatase 2A (PP2A) regulatory B unit. The B subunits determine the substrate specificity of the enzyme. | Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. | 0.984 |
CG4733 | mts | FBpp0300986 | FBpp0310062 | MIP22305p; CG4733 encodes a protein that is predicted to be the B"/PR72 subunit of Protein Phosphatase 2A (PP2A) regulatory B unit. The B subunits determine the substrate specificity of the enzyme. | Serine/threonine-protein phosphatase PP2A; Microtubule star (mts) encodes the catalytic subunit of protein phosphatase 2A. It is involved in various developmental processes and signaling pathways, such as Hh signaling and Wingless signaling; Belongs to the PPP phosphatase family. PP-2A subfamily. | 0.939 |
CG4733 | tws | FBpp0300986 | FBpp0311386 | MIP22305p; CG4733 encodes a protein that is predicted to be the B"/PR72 subunit of Protein Phosphatase 2A (PP2A) regulatory B unit. The B subunits determine the substrate specificity of the enzyme. | Protein phosphatase PP2A 55 kDa regulatory subunit; Could perform a substrate recognition function or could be responsible for targeting the enzyme complex to the appropriate subcellular compartment. | 0.983 |
CG4733 | wdb | FBpp0300986 | FBpp0084575 | MIP22305p; CG4733 encodes a protein that is predicted to be the B"/PR72 subunit of Protein Phosphatase 2A (PP2A) regulatory B unit. The B subunits determine the substrate specificity of the enzyme. | Widerborst (wdb) encodes a B' regulatory subunit of the serine/threonine phosphatase complex PP2A. It regulates Hedgehog, protein kinase B and insulin receptor signaling pathways. | 0.979 |
CG4733 | wrd | FBpp0300986 | FBpp0082978 | MIP22305p; CG4733 encodes a protein that is predicted to be the B"/PR72 subunit of Protein Phosphatase 2A (PP2A) regulatory B unit. The B subunits determine the substrate specificity of the enzyme. | Well-rounded, isoform B; Well-rounded (wrd) encodes one of the two regulatory B' subunits of the protein phosphatase PP2A. It influences metabolism and growth via negative regulation of the InR/TOR signalling network. | 0.924 |
Pp2A-29B | CG32568 | FBpp0308836 | FBpp0310019 | Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. | Uncharacterized protein, isoform B; Protein phosphatase activator activity. It is involved in the biological process described with: regulation of protein autophosphorylation; signal transduction; protein dephosphorylation. | 0.989 |
Pp2A-29B | CG4733 | FBpp0308836 | FBpp0300986 | Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. | MIP22305p; CG4733 encodes a protein that is predicted to be the B"/PR72 subunit of Protein Phosphatase 2A (PP2A) regulatory B unit. The B subunits determine the substrate specificity of the enzyme. | 0.984 |
Pp2A-29B | endos | FBpp0308836 | FBpp0305266 | Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. | Endosulfine, isoform A; Endosulfine (endos) encodes a protein that, after its phosphorylation by the kinase encoded by gwl, inhibits the phosphatase encoded by tws. This inhibition is important for the entry of cells into M phase during the cell cycle. | 0.642 |
Pp2A-29B | mts | FBpp0308836 | FBpp0310062 | Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. | Serine/threonine-protein phosphatase PP2A; Microtubule star (mts) encodes the catalytic subunit of protein phosphatase 2A. It is involved in various developmental processes and signaling pathways, such as Hh signaling and Wingless signaling; Belongs to the PPP phosphatase family. PP-2A subfamily. | 0.999 |
Pp2A-29B | tws | FBpp0308836 | FBpp0311386 | Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. | Protein phosphatase PP2A 55 kDa regulatory subunit; Could perform a substrate recognition function or could be responsible for targeting the enzyme complex to the appropriate subcellular compartment. | 0.999 |
Pp2A-29B | wdb | FBpp0308836 | FBpp0084575 | Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. | Widerborst (wdb) encodes a B' regulatory subunit of the serine/threonine phosphatase complex PP2A. It regulates Hedgehog, protein kinase B and insulin receptor signaling pathways. | 0.999 |
Pp2A-29B | wrd | FBpp0308836 | FBpp0082978 | Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. | Well-rounded, isoform B; Well-rounded (wrd) encodes one of the two regulatory B' subunits of the protein phosphatase PP2A. It influences metabolism and growth via negative regulation of the InR/TOR signalling network. | 0.996 |
Sse | grp | FBpp0076831 | FBpp0080443 | LD08709p; Separase (Sse) encodes an endoprotease. Together with the product of thr, it forms a complex which cleaves a subunit of the cohesin complex during meiosis, thereby allowing separation of the sister chromatids. | Serine/threonine-protein kinase grp; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. May phosphorylate the CDC25 phosphatase stg, which promotes its degradation. This results in increased inhibitory tyrosine phosphorylation of Cdk1-cyclin complexes and consequent inhibition of cell cycle progression. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase [...] | 0.630 |