STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ak3GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (216 aa)    
Predicted Functional Partners:
Adk1
AT16233p; Adenosine kinase activity. It is involved in the biological process described with: purine ribonucleoside salvage; AMP biosynthetic process.
  
 0.946
AdSL
Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.946
Adk3
GM02629p; Adenosine kinase activity.
  
 0.944
Adk2
Adenosine kinase activity. It is involved in the biological process described with: purine ribonucleoside salvage; AMP biosynthetic process.
  
 0.944
Aprt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.943
awd
Nucleoside diphosphate kinase; Abnormal wing discs (awd) encodes a nucleotide diphosphate kinase that regulates with the product of shi the endocytosis of different surface proteins (e.g. those encoded by N, btl, Pvr, and shg). During development, it regulates morphogenesis of trachea, follicular epithelium, and imaginal discs and contributes to neurotransmission and border cell migration; Belongs to the NDK family.
  
 0.929
RnrL
Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
 0.928
nmdyn-D6
Nucleoside diphosphate kinase activity. It is involved in the biological process described with: GTP biosynthetic process; nucleoside triphosphate biosynthetic process; CTP biosynthetic process; UTP biosynthetic process; nucleoside diphosphate phosphorylation.
  
 0.922
nmdyn-D7
FI21821p1; ATP binding; nucleoside diphosphate kinase activity. It is involved in the biological process described with: nucleoside diphosphate phosphorylation; UTP biosynthetic process; CTP biosynthetic process; GTP biosynthetic process; nucleoside triphosphate biosynthetic process; Belongs to the NDK family.
  
 0.922
CG15547
NDK domain-containing protein; It is involved in the biological process described with: negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway.
  
 0.922
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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