STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fer3Protein Fer3; Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins (By similarity). (195 aa)    
Predicted Functional Partners:
Lmx1a
LIM homeobox transcription factor 1 alpha, isoform B; RNA polymerase II regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: neuron differentiation; positive regulation of transcription by RNA polymerase II.
   
 
 0.495
CG5037
Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.
      
 0.493
da
Daughterless (da) encodes a class I bHLH protein important for sex determination and dosage compensation by controlling the feminizing switch gene Sxl. It participates in transcriptional regulation of a wide variety processes, including oogenesis, neurogenesis, myogenesis and cell proliferation.
    
 
 0.486
tx
Helix-loop-helix protein delilah; Taxi (tx) encodes a transcription factor that affects cell adhesion by regulating the expression of mys. It is involved in the development of multiple organs and cell-types including tendon cells, chordotonal organs and the wing.
   
  
 0.480
AstCC
Allatostatin double C, isoform C; Hormone activity.
      
 0.438
CG8128
FI03680p; NAD binding; ADP-ribose diphosphatase activity; NADH pyrophosphatase activity. It is involved in the biological process described with: signal transduction; Belongs to the Nudix hydrolase family.
      
 0.432
CG1578
LD05643p; Diphthine-ammonia ligase activity. It is involved in the biological process described with: peptidyl-diphthamide biosynthetic process from peptidyl-histidine.
      
 0.430
CG7639
SAM50-like protein CG7639; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family.
      
 0.422
Hr38
Hormone receptor-like in 38 (Hr38) encodes a protein that can heterodimerize with the U adult cuticle and for the proper uptake and storage of glycogen in larvae; Belongs to the nuclear hormone receptor family. NR4 subfamily.
      
 0.405
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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