STRINGSTRING
Hsp70Bc protein (fruit fly) - STRING interaction network
"Hsp70Bc" - Heat-shock-protein-70Bc in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hsp70BcHeat-shock-protein-70Bc (641 aa)    
Predicted Functional Partners:
Hsp22
Heat shock protein 22 (174 aa)
     
 
  0.999
Hsp68
Heat shock protein 68 (635 aa)
   
   
0.999
Hsp70Ab
Heat-shock-protein-70Ab (642 aa)
   
   
0.999
DnaJ-1
DnaJ-like-1 (334 aa)
 
 
  0.997
Hsp83
Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Together with Hop and piwi, mediates canalization, also known as developm [...] (717 aa)
     
 
  0.991
r
Rudimentary; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (2224 aa)
   
 
  0.978
P58IPK
P58IPK (498 aa)
   
 
  0.976
Roe1
Roe1; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity) (213 aa)
   
 
  0.975
aux
Auxillin (1165 aa)
     
 
  0.965
Hsp26
Protein binding (208 aa)
     
 
  0.965
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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