node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AstC | CCHa1 | FBpp0079821 | FBpp0112144 | Allatostatin C (AstC) encodes a myotropic factor involved in heart rate decrease. | Neuropeptide CCHamide-1; Ligand for the CCHamide-1 receptor CCHa1-R. | 0.850 |
AstC | CCHa2 | FBpp0079821 | FBpp0292355 | Allatostatin C (AstC) encodes a myotropic factor involved in heart rate decrease. | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | 0.676 |
AstC | Ilp3 | FBpp0079821 | FBpp0076102 | Allatostatin C (AstC) encodes a myotropic factor involved in heart rate decrease. | Insulin-like peptide 3 (Ilp3) encodes a peptide involved in the insulin signaling pathway, the sugar-mediated activation of TOR signaling, sleep and mating behavior in females. | 0.533 |
AstC | NPF | FBpp0079821 | FBpp0304075 | Allatostatin C (AstC) encodes a myotropic factor involved in heart rate decrease. | Neuropeptide F; Integral part of the sensory system that mediates food signaling, providing the neural basis for the regulation of food response; coordinates larval foraging and social behavior changes during development. Required in dopaminergic (DA) neurons that innervate the mushroom body for satiety to suppress appetitive memory performance; a key factor in the internal state of hunger in the brain. NPF neurons coordinately modulate diverse sensory and motor neurons important for feeding, flight, and locomotion. NPF/NPFR pathway exerts its suppressive effect on larval aversion to d [...] | 0.841 |
CCHa1 | AstC | FBpp0112144 | FBpp0079821 | Neuropeptide CCHamide-1; Ligand for the CCHamide-1 receptor CCHa1-R. | Allatostatin C (AstC) encodes a myotropic factor involved in heart rate decrease. | 0.850 |
CCHa1 | CCHa2 | FBpp0112144 | FBpp0292355 | Neuropeptide CCHamide-1; Ligand for the CCHamide-1 receptor CCHa1-R. | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | 0.838 |
CCHa1 | CCHa2-R | FBpp0112144 | FBpp0423126 | Neuropeptide CCHamide-1; Ligand for the CCHamide-1 receptor CCHa1-R. | Neuropeptide CCHamide-2 receptor; Receptor for the neuropeptide CCHamide-2. Belongs to the G-protein coupled receptor 1 family. | 0.679 |
CCHa1 | Ilp3 | FBpp0112144 | FBpp0076102 | Neuropeptide CCHamide-1; Ligand for the CCHamide-1 receptor CCHa1-R. | Insulin-like peptide 3 (Ilp3) encodes a peptide involved in the insulin signaling pathway, the sugar-mediated activation of TOR signaling, sleep and mating behavior in females. | 0.426 |
CCHa1 | NPF | FBpp0112144 | FBpp0304075 | Neuropeptide CCHamide-1; Ligand for the CCHamide-1 receptor CCHa1-R. | Neuropeptide F; Integral part of the sensory system that mediates food signaling, providing the neural basis for the regulation of food response; coordinates larval foraging and social behavior changes during development. Required in dopaminergic (DA) neurons that innervate the mushroom body for satiety to suppress appetitive memory performance; a key factor in the internal state of hunger in the brain. NPF neurons coordinately modulate diverse sensory and motor neurons important for feeding, flight, and locomotion. NPF/NPFR pathway exerts its suppressive effect on larval aversion to d [...] | 0.745 |
CCHa2 | AstC | FBpp0292355 | FBpp0079821 | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | Allatostatin C (AstC) encodes a myotropic factor involved in heart rate decrease. | 0.676 |
CCHa2 | CCHa1 | FBpp0292355 | FBpp0112144 | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | Neuropeptide CCHamide-1; Ligand for the CCHamide-1 receptor CCHa1-R. | 0.838 |
CCHa2 | CCHa2-R | FBpp0292355 | FBpp0423126 | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | Neuropeptide CCHamide-2 receptor; Receptor for the neuropeptide CCHamide-2. Belongs to the G-protein coupled receptor 1 family. | 0.896 |
CCHa2 | Gbp1 | FBpp0292355 | FBpp0086139 | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | Growth-blocking peptide 1 (Gbp1) encodes a cytokine that regulates the humoral immune response. | 0.706 |
CCHa2 | Gbp2 | FBpp0292355 | FBpp0311626 | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | Growth-blocking peptide 2, isoform A; N-acetyltransferase activity; cytokine activity. It is involved in the biological process described with: signal transduction. | 0.677 |
CCHa2 | Ilp3 | FBpp0292355 | FBpp0076102 | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | Insulin-like peptide 3 (Ilp3) encodes a peptide involved in the insulin signaling pathway, the sugar-mediated activation of TOR signaling, sleep and mating behavior in females. | 0.666 |
CCHa2 | Ilp5 | FBpp0292355 | FBpp0422627 | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | Insulin-like peptide 5 (Ilp5) encodes a peptide involved in the insulin signaling pathway, sleep and mating behavior in females; Belongs to the insulin family. | 0.675 |
CCHa2 | Lst | FBpp0292355 | FBpp0297147 | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | Limostatin, isoform B; Limostatin (Lst) encodes a peptide hormone produced by endocrine corpora cardiaca cells during starvation. It suppresses insulin production and secretion from insulin-producing cells by signaling through the G-protein coupled receptor encoded by PK1-R. | 0.663 |
CCHa2 | NPF | FBpp0292355 | FBpp0304075 | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | Neuropeptide F; Integral part of the sensory system that mediates food signaling, providing the neural basis for the regulation of food response; coordinates larval foraging and social behavior changes during development. Required in dopaminergic (DA) neurons that innervate the mushroom body for satiety to suppress appetitive memory performance; a key factor in the internal state of hunger in the brain. NPF neurons coordinately modulate diverse sensory and motor neurons important for feeding, flight, and locomotion. NPF/NPFR pathway exerts its suppressive effect on larval aversion to d [...] | 0.668 |
CCHa2 | upd2 | FBpp0292355 | FBpp0423083 | Neuropeptide CCHamide-2; Ligand for the CCHamide-2 receptor CCHa2-R. In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth. In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides. | Unpaired 2 (upd2) encodes a secreted molecule that acts at a distance as a ligand for the JAK/STAT signal transduction pathway. upd2 mutants are viable due to redundancy with other Upd-family genes. | 0.662 |
CCHa2-R | CCHa1 | FBpp0423126 | FBpp0112144 | Neuropeptide CCHamide-2 receptor; Receptor for the neuropeptide CCHamide-2. Belongs to the G-protein coupled receptor 1 family. | Neuropeptide CCHamide-1; Ligand for the CCHamide-1 receptor CCHa1-R. | 0.679 |