node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atpalpha | Sap47 | FBpp0088502 | FBpp0082658 | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | 0.530 |
Bdbt | Sap47 | FBpp0083435 | FBpp0082658 | Bride of doubletime (Bdbt) encodes a protein that binds to a nuclear localization signal in the product of dco and is necessary for normal circadian dco activity on the product of per. The product of Bdbt also accumulates in cytosolic foci in photoreceptors during the middle of the night. | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | 0.507 |
Bdbt | alpha-Man-Ia | FBpp0083435 | FBpp0288908 | Bride of doubletime (Bdbt) encodes a protein that binds to a nuclear localization signal in the product of dco and is necessary for normal circadian dco activity on the product of per. The product of Bdbt also accumulates in cytosolic foci in photoreceptors during the middle of the night. | Mannosyl-oligosaccharide alpha-1,2-mannosidase IA; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). | 0.697 |
CG32683 | Mitofilin | FBpp0071397 | FBpp0307187 | FI20035p1; G protein-coupled receptor binding. It is involved in the biological process described with: G protein-coupled receptor internalization. | MICOS complex subunit Mic60; Mitofilin (Mitofilin) encodes a major component of the mitochondrial contact site (MICOS) complex, which is located at the mitochondrial crista junctions. It maintains crista structure and contact sites, and regulates mitochondrial motility. Mitofilin product functions downstream of the kinase encoded by Pink1, to maintain mitochondrial structure and cellular homeostasis. | 0.606 |
CG32683 | Sap47 | FBpp0071397 | FBpp0082658 | FI20035p1; G protein-coupled receptor binding. It is involved in the biological process described with: G protein-coupled receptor internalization. | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | 0.471 |
Cbp53E | Csp | FBpp0086204 | FBpp0311238 | Calbindin-32; Calbindin 53E (Cbp53E) encodes a 6 EF-hand domain-containing protein that regulates neuronal development. | DnaJ homolog subfamily C member 5 homolog; Cysteine string protein (Csp) encodes a synaptic vesicle-associated co-chaperone of Hsc70 that is vital for presynaptic proteostasis and maintenance of synaptic function. The substartes of the product of Csp include SNARE proteins and the product of shi, which mediate synaptic vesicle exo- and endocytosis respectively. | 0.408 |
Cbp53E | Sap47 | FBpp0086204 | FBpp0082658 | Calbindin-32; Calbindin 53E (Cbp53E) encodes a 6 EF-hand domain-containing protein that regulates neuronal development. | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | 0.622 |
Cbp53E | Syn | FBpp0086204 | FBpp0099901 | Calbindin-32; Calbindin 53E (Cbp53E) encodes a 6 EF-hand domain-containing protein that regulates neuronal development. | Synapsin-1; Synapsin (Syn) encodes a phosphoprotein associated with synaptic vesicles. It interacts with the endocytic scaffolding protein encoded by Dap160. Phosphorylation of synapsin at serine 6 is required for associative short-term learning/memory and short-term olfactory habituation. It is important for outgrowth of synaptic boutons at the larval neuromuscular junction. | 0.461 |
Csp | Cbp53E | FBpp0311238 | FBpp0086204 | DnaJ homolog subfamily C member 5 homolog; Cysteine string protein (Csp) encodes a synaptic vesicle-associated co-chaperone of Hsc70 that is vital for presynaptic proteostasis and maintenance of synaptic function. The substartes of the product of Csp include SNARE proteins and the product of shi, which mediate synaptic vesicle exo- and endocytosis respectively. | Calbindin-32; Calbindin 53E (Cbp53E) encodes a 6 EF-hand domain-containing protein that regulates neuronal development. | 0.408 |
Csp | Sap47 | FBpp0311238 | FBpp0082658 | DnaJ homolog subfamily C member 5 homolog; Cysteine string protein (Csp) encodes a synaptic vesicle-associated co-chaperone of Hsc70 that is vital for presynaptic proteostasis and maintenance of synaptic function. The substartes of the product of Csp include SNARE proteins and the product of shi, which mediate synaptic vesicle exo- and endocytosis respectively. | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | 0.602 |
Csp | Syn | FBpp0311238 | FBpp0099901 | DnaJ homolog subfamily C member 5 homolog; Cysteine string protein (Csp) encodes a synaptic vesicle-associated co-chaperone of Hsc70 that is vital for presynaptic proteostasis and maintenance of synaptic function. The substartes of the product of Csp include SNARE proteins and the product of shi, which mediate synaptic vesicle exo- and endocytosis respectively. | Synapsin-1; Synapsin (Syn) encodes a phosphoprotein associated with synaptic vesicles. It interacts with the endocytic scaffolding protein encoded by Dap160. Phosphorylation of synapsin at serine 6 is required for associative short-term learning/memory and short-term olfactory habituation. It is important for outgrowth of synaptic boutons at the larval neuromuscular junction. | 0.662 |
Csp | alpha-Man-Ia | FBpp0311238 | FBpp0288908 | DnaJ homolog subfamily C member 5 homolog; Cysteine string protein (Csp) encodes a synaptic vesicle-associated co-chaperone of Hsc70 that is vital for presynaptic proteostasis and maintenance of synaptic function. The substartes of the product of Csp include SNARE proteins and the product of shi, which mediate synaptic vesicle exo- and endocytosis respectively. | Mannosyl-oligosaccharide alpha-1,2-mannosidase IA; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). | 0.417 |
Mitofilin | CG32683 | FBpp0307187 | FBpp0071397 | MICOS complex subunit Mic60; Mitofilin (Mitofilin) encodes a major component of the mitochondrial contact site (MICOS) complex, which is located at the mitochondrial crista junctions. It maintains crista structure and contact sites, and regulates mitochondrial motility. Mitofilin product functions downstream of the kinase encoded by Pink1, to maintain mitochondrial structure and cellular homeostasis. | FI20035p1; G protein-coupled receptor binding. It is involved in the biological process described with: G protein-coupled receptor internalization. | 0.606 |
Mitofilin | Sap47 | FBpp0307187 | FBpp0082658 | MICOS complex subunit Mic60; Mitofilin (Mitofilin) encodes a major component of the mitochondrial contact site (MICOS) complex, which is located at the mitochondrial crista junctions. It maintains crista structure and contact sites, and regulates mitochondrial motility. Mitofilin product functions downstream of the kinase encoded by Pink1, to maintain mitochondrial structure and cellular homeostasis. | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | 0.536 |
Sap47 | Atpalpha | FBpp0082658 | FBpp0088502 | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | Sodium/potassium-transporting ATPase subunit alpha; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | 0.530 |
Sap47 | Bdbt | FBpp0082658 | FBpp0083435 | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | Bride of doubletime (Bdbt) encodes a protein that binds to a nuclear localization signal in the product of dco and is necessary for normal circadian dco activity on the product of per. The product of Bdbt also accumulates in cytosolic foci in photoreceptors during the middle of the night. | 0.507 |
Sap47 | CG32683 | FBpp0082658 | FBpp0071397 | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | FI20035p1; G protein-coupled receptor binding. It is involved in the biological process described with: G protein-coupled receptor internalization. | 0.471 |
Sap47 | Cbp53E | FBpp0082658 | FBpp0086204 | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | Calbindin-32; Calbindin 53E (Cbp53E) encodes a 6 EF-hand domain-containing protein that regulates neuronal development. | 0.622 |
Sap47 | Csp | FBpp0082658 | FBpp0311238 | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | DnaJ homolog subfamily C member 5 homolog; Cysteine string protein (Csp) encodes a synaptic vesicle-associated co-chaperone of Hsc70 that is vital for presynaptic proteostasis and maintenance of synaptic function. The substartes of the product of Csp include SNARE proteins and the product of shi, which mediate synaptic vesicle exo- and endocytosis respectively. | 0.602 |
Sap47 | Mitofilin | FBpp0082658 | FBpp0307187 | Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. | MICOS complex subunit Mic60; Mitofilin (Mitofilin) encodes a major component of the mitochondrial contact site (MICOS) complex, which is located at the mitochondrial crista junctions. It maintains crista structure and contact sites, and regulates mitochondrial motility. Mitofilin product functions downstream of the kinase encoded by Pink1, to maintain mitochondrial structure and cellular homeostasis. | 0.536 |