STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OdjLD33778p; DNA binding; zinc ion binding. It is involved in the biological process described with: heterochromatin organization involved in chromatin silencing. (430 aa)    
Predicted Functional Partners:
vers
Versatile (vers) encodes a component of the heterochromatin protein 1 complex that regulates adult testis germline stem cell fate.
   
 
 0.996
dgrn
Degringolade, isoform A; Degringolade (dgrn) encodes a SUMO-Targeted ubiquitin ligase. During development it is required for Notch signaling and patterning. It contributes to transcriptional regulation, DNA repair, and cytoskeleton dynamics.
   
   0.994
AP-1mu
Adaptor Protein complex 1, mu subunit (AP-1mu) encodes a clathrin adaptor involved in intracellular transport. It controls the trafficking of proteins, including the products of N and spdo.
   
   0.994
Ank2
Ankyrin 2, isoform U; Ankyrin 2 (Ank2) encodes a cytoskeletal binding protein required for proper function of the product of beta-Spec via direct interaction. It contributes to the regulation of short-term memory, sound perception, microtubule cytoskeleton and neuromuscular junction development and synapsis.
    
   0.994
CG8851
Uncharacterized protein, isoform C.
    
   0.994
CG1815
GH01331p; Methylated histone binding; lysine-acetylated histone binding. It is involved in the biological process described with: regulation of transcription, DNA-templated.
   
 
 0.802
Sry-beta
Serendipity locus protein beta; Binds to the consensus DNA sequence 5'-YCAGAGATGCGCA-3'.
  
  
 0.783
ADD1
ADD domain-containing protein 1 (ADD1) encodes a strong Heterochromatin Protein 1 interactor that interacts with methylated H3K9 silencing marks in heterochromatin.
   
 
 0.702
E(var)3-9
Enhancer of variegation 3-9; Nucleic acid binding; zinc ion binding. It is involved in the biological process described with: regulation of gene expression; chromatin maintenance.
   
  
 0.679
CG12219
LD26135p; Zinc ion binding; DNA-binding transcription factor activity; transcription regulatory region sequence-specific DNA binding; DNA binding. It is involved in the biological process described with: regulation of gene expression; regulation of transcription, DNA-templated.
   
  
 0.674
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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