node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Act57B | Act87E | FBpp0071448 | FBpp0312019 | Actin-57B; Actin 57B (Act57B) is one of several actin genes in the Drosophila genome, and one of the few that encode myofibrillar actin. This essential gene is a transcriptional target of Mef2 and Cf2 and is expressed in all embryonic muscles and a subset of adult muscle. | Actin-87E; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | 0.871 |
Act57B | CG5023 | FBpp0071448 | FBpp0083275 | Actin-57B; Actin 57B (Act57B) is one of several actin genes in the Drosophila genome, and one of the few that encode myofibrillar actin. This essential gene is a transcriptional target of Mef2 and Cf2 and is expressed in all embryonic muscles and a subset of adult muscle. | GH21596p; Actin binding. It is involved in the biological process described with: actomyosin structure organization. | 0.666 |
Act57B | CG5177 | FBpp0071448 | FBpp0304792 | Actin-57B; Actin 57B (Act57B) is one of several actin genes in the Drosophila genome, and one of the few that encode myofibrillar actin. This essential gene is a transcriptional target of Mef2 and Cf2 and is expressed in all embryonic muscles and a subset of adult muscle. | Trehalose 6-phosphate phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | 0.763 |
Act57B | Mlc1 | FBpp0071448 | FBpp0310544 | Actin-57B; Actin 57B (Act57B) is one of several actin genes in the Drosophila genome, and one of the few that encode myofibrillar actin. This essential gene is a transcriptional target of Mef2 and Cf2 and is expressed in all embryonic muscles and a subset of adult muscle. | Myosin light chain alkali; Microfilament motor activity; calcium ion binding. It is involved in the biological process described with: muscle contraction; mesoderm development. | 0.947 |
Act57B | Mp20 | FBpp0071448 | FBpp0311634 | Actin-57B; Actin 57B (Act57B) is one of several actin genes in the Drosophila genome, and one of the few that encode myofibrillar actin. This essential gene is a transcriptional target of Mef2 and Cf2 and is expressed in all embryonic muscles and a subset of adult muscle. | Muscle-specific protein 20; It is involved in the biological process described with: myoblast fusion; regulation of myoblast fusion. | 0.924 |
Act57B | Prm | FBpp0071448 | FBpp0076320 | Actin-57B; Actin 57B (Act57B) is one of several actin genes in the Drosophila genome, and one of the few that encode myofibrillar actin. This essential gene is a transcriptional target of Mef2 and Cf2 and is expressed in all embryonic muscles and a subset of adult muscle. | Paramyosin, long form; Paramyosin (Prm) encodes a muscle protein found only in invertebrates. It dimerizes into a coiled-coil that occupies the interior of the thick filament. Its role is thought to be structural, although it can be phosphorylated and this is important for muscle function. | 0.784 |
Act57B | Tm2 | FBpp0071448 | FBpp0089270 | Actin-57B; Actin 57B (Act57B) is one of several actin genes in the Drosophila genome, and one of the few that encode myofibrillar actin. This essential gene is a transcriptional target of Mef2 and Cf2 and is expressed in all embryonic muscles and a subset of adult muscle. | Tropomyosin-2; Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. May also regulate motor systems required to maintain nuclear integrity and apico-basal polarity during embryogenesis. | 0.922 |
Act57B | up | FBpp0071448 | FBpp0301821 | Actin-57B; Actin 57B (Act57B) is one of several actin genes in the Drosophila genome, and one of the few that encode myofibrillar actin. This essential gene is a transcriptional target of Mef2 and Cf2 and is expressed in all embryonic muscles and a subset of adult muscle. | Troponin T, skeletal muscle; Upheld (up) encodes the striated muscle protein Troponin T. Troponins T, C and I form a regulatory complex with Tropomyosin that is found at regular intervals along the thin (F-actin) filaments of the muscle sarcomere. | 0.732 |
Act87E | Act57B | FBpp0312019 | FBpp0071448 | Actin-87E; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Actin-57B; Actin 57B (Act57B) is one of several actin genes in the Drosophila genome, and one of the few that encode myofibrillar actin. This essential gene is a transcriptional target of Mef2 and Cf2 and is expressed in all embryonic muscles and a subset of adult muscle. | 0.871 |
Act87E | CG5023 | FBpp0312019 | FBpp0083275 | Actin-87E; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | GH21596p; Actin binding. It is involved in the biological process described with: actomyosin structure organization. | 0.725 |
Act87E | CG5177 | FBpp0312019 | FBpp0304792 | Actin-87E; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Trehalose 6-phosphate phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | 0.593 |
Act87E | Mlc1 | FBpp0312019 | FBpp0310544 | Actin-87E; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Myosin light chain alkali; Microfilament motor activity; calcium ion binding. It is involved in the biological process described with: muscle contraction; mesoderm development. | 0.884 |
Act87E | Mp20 | FBpp0312019 | FBpp0311634 | Actin-87E; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Muscle-specific protein 20; It is involved in the biological process described with: myoblast fusion; regulation of myoblast fusion. | 0.878 |
Act87E | Prm | FBpp0312019 | FBpp0076320 | Actin-87E; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Paramyosin, long form; Paramyosin (Prm) encodes a muscle protein found only in invertebrates. It dimerizes into a coiled-coil that occupies the interior of the thick filament. Its role is thought to be structural, although it can be phosphorylated and this is important for muscle function. | 0.844 |
Act87E | Tm2 | FBpp0312019 | FBpp0089270 | Actin-87E; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Tropomyosin-2; Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. May also regulate motor systems required to maintain nuclear integrity and apico-basal polarity during embryogenesis. | 0.879 |
Act87E | TpnC25D | FBpp0312019 | FBpp0312108 | Actin-87E; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | 0.606 |
Act87E | up | FBpp0312019 | FBpp0301821 | Actin-87E; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Troponin T, skeletal muscle; Upheld (up) encodes the striated muscle protein Troponin T. Troponins T, C and I form a regulatory complex with Tropomyosin that is found at regular intervals along the thin (F-actin) filaments of the muscle sarcomere. | 0.585 |
CG5023 | Act57B | FBpp0083275 | FBpp0071448 | GH21596p; Actin binding. It is involved in the biological process described with: actomyosin structure organization. | Actin-57B; Actin 57B (Act57B) is one of several actin genes in the Drosophila genome, and one of the few that encode myofibrillar actin. This essential gene is a transcriptional target of Mef2 and Cf2 and is expressed in all embryonic muscles and a subset of adult muscle. | 0.666 |
CG5023 | Act87E | FBpp0083275 | FBpp0312019 | GH21596p; Actin binding. It is involved in the biological process described with: actomyosin structure organization. | Actin-87E; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | 0.725 |
CG5023 | CG5177 | FBpp0083275 | FBpp0304792 | GH21596p; Actin binding. It is involved in the biological process described with: actomyosin structure organization. | Trehalose 6-phosphate phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | 0.750 |