STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG4335Uncharacterized protein; Trimethyllysine dioxygenase activity; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; carnitine biosynthetic process. (364 aa)    
Predicted Functional Partners:
CG5321
Uncharacterized protein, isoform B; Gamma-butyrobetaine dioxygenase activity. It is involved in the biological process described with: carnitine biosynthetic process; oxidation-reduction process.
  
 
0.936
CG10814
LP01339p; Gamma-butyrobetaine dioxygenase activity. It is involved in the biological process described with: carnitine biosynthetic process; oxidation-reduction process.
  
 
0.926
Aldh
Aldehyde dehydrogenase (Aldh) encodes an NAD[+] dependent mitochondrial aldehyde dehydrogenase. Its functions include detoxifying endogenous aldehydes generated by lipid peroxidation, and detoxifying acetaldehyde derived from dietary ethanol.
   
 
 0.915
CG31075
Uncharacterized protein, isoform B; Aldehyde dehydrogenase (NAD+) activity. It is involved in the biological process described with: oxidation-reduction process; pyruvate metabolic process.
   
 
 0.913
Aldh7A1
Aldehyde dehydrogenase 7 family member A1; Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: oxidation-reduction process.
   
 
 0.908
CG6550
Threonylcarbamoyladenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. Belongs to the methylthiotransferase family. CDKAL1 subfamily.
      
 0.634
CG10184
LD34157p; L-allo-threonine aldolase activity. It is involved in the biological process described with: threonine catabolic process; glycine biosynthetic process.
   
  
 0.603
Gfrl
Glial cell line-derived neurotrophic family receptor-like, isoform E; Signaling receptor activity; cell adhesion molecule binding. It is involved in the biological process described with: nervous system development.
 
    
 0.574
Cp7Fc
Chorion protein c at 7F (Cp7Fc) belongs to a family of nine Chorion protein genes clustered in two chromosomes (X and 3rd). It is expressed in the follicle cells in a dynamic pattern.
      
 0.531
eIF3g2
Eukaryotic translation initiation factor 3 subunit G-2; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.
      
 0.530
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.