STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rab1FI01544p; Rab1 (Rab1) encodes a small GTPase which regulates endoplasmic reticulum to Golgi and intra Golgi trafficking through different effectors. It has been involved in Notch signaling, cell migration, autophagy and cytokinesis. (205 aa)    
Predicted Functional Partners:
Gdi
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 0.984
Bet3
Trafficking protein particle complex subunit; Blocked early in transport 3 (Bet3) encodes a protein involved in dsRNA transport; Belongs to the TRAPP small subunits family. BET3 subfamily.
   
 0.979
p115
General vesicular transport factor p115; Essential for maintaining the architecture of the Golgi stacks and for normal organization of the transitional endoplasmic reticulum (tER). Required for both the formation of the Golgi stacks and the maintenance of the individual cisternae. Belongs to the VDP/USO1/EDE1 family.
   
 0.973
Bet5
Trafficking protein particle complex subunit; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: Golgi vesicle transport; vesicle-mediated transport; endoplasmic reticulum to Golgi vesicle-mediated transport; Belongs to the TRAPP small subunits family.
   
 0.969
Trs23
Trafficking protein particle complex subunit; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: endoplasmic reticulum to Golgi vesicle-mediated transport; vesicle-mediated transport; Golgi vesicle transport; Belongs to the TRAPP small subunits family.
    
 0.960
Trs31
Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi.
    
 0.945
Trs20
Probable trafficking protein particle complex subunit 2; May play a role in vesicular transport from endoplasmic reticulum to Golgi. Involved in dsRNA uptake.
   
 0.942
l(3)76BDm
Lethal (3) 76BDm, isoform A; It is involved in the biological process described with: autophagy of peroxisome; Golgi vesicle transport; endoplasmic reticulum to Golgi vesicle-mediated transport; protein localization to phagophore assembly site; autophagosome assembly.
    
 0.941
garz
Gartenzwerg, isoform B; Gartenzwerg (garz) encodes a guanine nucleotide exchange factor localized to the cis-Golgi apparatus. The roles of the product of garz include membrane and protein trafficking between the Golgi apparatus and the endoplasmic reticulum. It is required for epithelial morphogenesis in the embryo.
    
 0.939
CG17883
RE60063p; GTPase activator activity; Rab GTPase binding. It is involved in the biological process described with: regulation of GTPase activity; endoplasmic reticulum to Golgi vesicle-mediated transport.
   
 0.925
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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