STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG7059Phosphoglycerate mutase activity. It is involved in the biological process described with: glycolytic process; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (267 aa)    
Predicted Functional Partners:
Eno
Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family.
  
 0.990
Pgk
Phosphoglycerate kinase (Pgk) encodes an enzyme involved in myoblast fusion; Belongs to the phosphoglycerate kinase family.
   
 0.987
Pgi
Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis.
  
 
 0.971
Tpi
Triose phosphate isomerase (Tpi) encodes a soluble metabolic protein dimer that functions in glycolysis catalyzing the isomerization between dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, which is essential for efficient ATP production.
  
 
 0.955
Ald1
Fructose-bisphosphate aldolase; May take part in developmental stage-specific or tissue -specific sugar-phosphate metabolisms. Protein acts on two substrates fructose 1,6-bisphosphate and fructose 1-phosphate (like other class I aldolases).
  
 0.921
CG8036
LP07963p; Transketolase activity; thiamine pyrophosphate binding. It is involved in the biological process described with: regulation of chromatin silencing.
   
 0.917
CG6287
GH03305p; NAD binding; phosphoglycerate dehydrogenase activity. It is involved in the biological process described with: cellular amino acid metabolic process; oxidation-reduction process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 0.916
Ald2
Fructose-bisphosphate aldolase activity. It is involved in the biological process described with: fructose 1,6-bisphosphate metabolic process; glycolytic process.
  
 0.916
Taldo
Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.914
CG9961
Phosphoglycerate kinase activity; ADP binding; ATP binding. It is involved in the biological process described with: positive regulation of oxidative phosphorylation; gluconeogenesis; glycolytic process.
   
 
 0.911
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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