STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCT1T-complex protein 1 subunit alpha; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (557 aa)    
Predicted Functional Partners:
CCT2
Chaperonin containing TCP1 subunit 2; ATP binding; unfolded protein binding. It is involved in the biological process described with: protein folding.
   
0.999
CCT6
Chaperonin containing TCP1 subunit 6; ATP binding; unfolded protein binding. It is involved in the biological process described with: mitotic cell cycle; protein folding; centriole replication.
   
0.999
CCT4
T-complex protein 1 subunit delta; Unfolded protein binding; ATP binding. It is involved in the biological process described with: protein folding.
   
0.999
CCT7
T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
   
0.999
CCT3
T-complex protein 1 subunit gamma; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
   
0.999
CCT5
Chaperonin containing TCP1 subunit 5 (CCT5) encodes a component of the TCP-1 ring complex (TRiC) chaperonin. It is involved in myofibril organization maintenance, cardiac physiological rhythm and lifespan determination.
   
0.999
CCT8
Chaperonin containing TCP1 subunit 8; Unfolded protein binding; ATP binding. It is involved in the biological process described with: protein folding.
   
0.999
CG12507
Uncharacterized protein.
   
 
 0.981
viaf
Viral IAP-associated factor homolog; Modulates the activation of caspases during apoptosis. Belongs to the phosducin family.
   
 
 0.957
Hsc70-3
Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct folding of proteins and degradation of misfolded proteins (By similarity). Acts as a key repressor of the unfolded protein response (UPR) (By similarity).
  
 
 0.904
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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