STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wfs1Wolfram syndrome 1 (872 aa)    
Predicted Functional Partners:
Gp93
Glycoprotein 93; ATP binding; unfolded protein binding. It is involved in the biological process described with: protein folding; endodermal digestive tract morphogenesis; response to stress; midgut development
     
 0.948
P58IPK
LD25575p; Protein kinase inhibitor activity
     
 0.931
Pdi
Protein disulfide-isomerase; Participates in the folding of proteins containing disulfide bonds
     
 0.921
Atf6
Atf6, isoform C; Sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding; protein homodimerization activity. It is involved in the biological process described with: regulation of transcription, DNA-templated
   
 0.911
dally
Division abnormally delayed (Dally) is a core protein of heparan sulfate proteoglycans of the glypican family. It acts as a co-receptor for growth factors and morphogens, such as FGFs, dpp, wg, hh and upd1, and affects signaling and distribution of these ligands. Dally's roles include wing development and germline stem cell maintenance
     
 0.911
CG1889
annotation not available
   
 
 0.904
CG1791
annotation not available
   
 
 0.904
CG30281
annotation not available
   
 
 0.904
CG6788
LP06940p; It is involved in the biological process described with: cell adhesion
   
 
 0.904
CG9500
annotation not available
   
 
 0.904
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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