node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG10340 | ND-30 | FBpp0082803 | FBpp0072975 | RE28913p; It is involved in the biological process described with: mitochondrial proton-transporting ATP synthase complex assembly. | NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: oxidation-reduction process; reactive oxygen species metabolic process; Belongs to the complex I 30 kDa subunit family. | 0.413 |
CG10340 | PTPMT1 | FBpp0082803 | FBpp0083844 | RE28913p; It is involved in the biological process described with: mitochondrial proton-transporting ATP synthase complex assembly. | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Lipid phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Protein phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Does not dephosphorylate Akt. | 0.430 |
CG14297 | PTPMT1 | FBpp0083110 | FBpp0083844 | IP09476p; Protein tyrosine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Lipid phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Protein phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Does not dephosphorylate Akt. | 0.476 |
CG14297 | Pten | FBpp0083110 | FBpp0289789 | IP09476p; Protein tyrosine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. | Phosphatase and tensin homolog (Pten) encodes a dual lipid and protein phosphatase that primarily counters the effects of the insulin-regulated lipid kinase, encoded by Pi3K92E. It inhibits cell growth, cell proliferation and cellular events controlling cytoskeletal and junctional rearrangements. | 0.506 |
CG14297 | pr | FBpp0083110 | FBpp0088417 | IP09476p; Protein tyrosine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. | 6-pyruvoyl tetrahydrobiopterin synthase; Required for pigment and biopterin synthesis. Belongs to the PTPS family. | 0.756 |
CG33331 | CG7718 | FBpp0082457 | FBpp0083097 | Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. | 0.463 |
CG33331 | CLS | FBpp0082457 | FBpp0084303 | Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. | Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. | 0.478 |
CG33331 | PTPMT1 | FBpp0082457 | FBpp0083844 | Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Lipid phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Protein phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Does not dephosphorylate Akt. | 0.936 |
CG33331 | Taz | FBpp0082457 | FBpp0086975 | Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. | Tafazzin (Taz) encodes a mitochondrial phospholipid-lysophospholipid transacylase that exchange acyl groups between cardiolipin molecules and other phospholipids. It plays a critical role in maintaining a normal cardiolipin composition required for optimal mitochondrial function. | 0.629 |
CG7718 | CG33331 | FBpp0083097 | FBpp0082457 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. | Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. | 0.463 |
CG7718 | CLS | FBpp0083097 | FBpp0084303 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. | Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. | 0.988 |
CG7718 | PTPMT1 | FBpp0083097 | FBpp0083844 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Lipid phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Protein phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Does not dephosphorylate Akt. | 0.638 |
CG7718 | Taz | FBpp0083097 | FBpp0086975 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. | Tafazzin (Taz) encodes a mitochondrial phospholipid-lysophospholipid transacylase that exchange acyl groups between cardiolipin molecules and other phospholipids. It plays a critical role in maintaining a normal cardiolipin composition required for optimal mitochondrial function. | 0.890 |
CLS | CG33331 | FBpp0084303 | FBpp0082457 | Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. | Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. | 0.478 |
CLS | CG7718 | FBpp0084303 | FBpp0083097 | Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. | 0.988 |
CLS | PTPMT1 | FBpp0084303 | FBpp0083844 | Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Lipid phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Protein phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Does not dephosphorylate Akt. | 0.737 |
CLS | Taz | FBpp0084303 | FBpp0086975 | Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. | Tafazzin (Taz) encodes a mitochondrial phospholipid-lysophospholipid transacylase that exchange acyl groups between cardiolipin molecules and other phospholipids. It plays a critical role in maintaining a normal cardiolipin composition required for optimal mitochondrial function. | 0.998 |
ND-30 | CG10340 | FBpp0072975 | FBpp0082803 | NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: oxidation-reduction process; reactive oxygen species metabolic process; Belongs to the complex I 30 kDa subunit family. | RE28913p; It is involved in the biological process described with: mitochondrial proton-transporting ATP synthase complex assembly. | 0.413 |
ND-30 | PTPMT1 | FBpp0072975 | FBpp0083844 | NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: oxidation-reduction process; reactive oxygen species metabolic process; Belongs to the complex I 30 kDa subunit family. | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Lipid phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Protein phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Does not dephosphorylate Akt. | 0.679 |
ND-30 | mRpS7 | FBpp0072975 | FBpp0304503 | NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: oxidation-reduction process; reactive oxygen species metabolic process; Belongs to the complex I 30 kDa subunit family. | 28S ribosomal protein S7, mitochondrial; Structural constituent of ribosome; rRNA binding; mRNA binding. It is involved in the biological process described with: mitochondrial translation; translation; ribosomal small subunit assembly; Belongs to the universal ribosomal protein uS7 family. | 0.672 |