node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG3515 | Cpsf100 | FBpp0077430 | FBpp0084726 | FI19335p1; Chromatin binding; histone methyltransferase activity (H3-K4 specific). It is involved in the biological process described with: histone H3-K4 trimethylation. | Probable cleavage and polyadenylation specificity factor subunit 2; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Required for the cotranscriptional processing of 3'- ends of polyadenylated and histone pre-mRNA. | 0.965 |
CG3515 | Cpsf160 | FBpp0077430 | FBpp0089163 | FI19335p1; Chromatin binding; histone methyltransferase activity (H3-K4 specific). It is involved in the biological process described with: histone H3-K4 trimethylation. | Cleavage and polyadenylation specificity factor subunit 1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity); Belongs to the CPSF1 family. | 0.965 |
CG3515 | Cpsf73 | FBpp0077430 | FBpp0083105 | FI19335p1; Chromatin binding; histone methyltransferase activity (H3-K4 specific). It is involved in the biological process described with: histone H3-K4 trimethylation. | Cleavage and polyadenylation specificity factor 73; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Has endonuclease activity and functions as mRNA 3'- end-processing endonuclease. Required for the cotranscriptional processing of 3'-ends of polyadenylated and histone pre-mRNA. Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lacta [...] | 0.970 |
CG3515 | Pp1alpha-96A | FBpp0077430 | FBpp0306442 | FI19335p1; Chromatin binding; histone methyltransferase activity (H3-K4 specific). It is involved in the biological process described with: histone H3-K4 trimethylation. | Serine/threonine-protein phosphatase alpha-1 isoform; Protein phosphatase 1alpha at 96A (Pp1alpha-96A) encodes a phosphatase involved in the regulation of Hedgehog and Wnt signaling pathways. | 0.885 |
CG3515 | Ssu72 | FBpp0077430 | FBpp0074516 | FI19335p1; Chromatin binding; histone methyltransferase activity (H3-K4 specific). It is involved in the biological process described with: histone H3-K4 trimethylation. | Ssu72 CTD phosphatase (Ssu72) encodes an RNA polymerase II C-terminal domain (CTD) phosphatase. Its phosphatase activity is important for RNAPII transcription and termination and for gene looping. It may also be involved in the regulation of sister chromatid cohesion. | 0.986 |
CG3515 | Wdr33 | FBpp0077430 | FBpp0078362 | FI19335p1; Chromatin binding; histone methyltransferase activity (H3-K4 specific). It is involved in the biological process described with: histone H3-K4 trimethylation. | WD repeat domain 33, isoform A; It is involved in the biological process described with: mRNA polyadenylation. | 0.980 |
CG3515 | Wdr82 | FBpp0077430 | FBpp0079266 | FI19335p1; Chromatin binding; histone methyltransferase activity (H3-K4 specific). It is involved in the biological process described with: histone H3-K4 trimethylation. | WD repeat domain 82 (Wdr82) encodes a component of the Compass complex, which performs K4 methylation of the histone encoded by His3. | 0.906 |
Cpsf100 | CG3515 | FBpp0084726 | FBpp0077430 | Probable cleavage and polyadenylation specificity factor subunit 2; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Required for the cotranscriptional processing of 3'- ends of polyadenylated and histone pre-mRNA. | FI19335p1; Chromatin binding; histone methyltransferase activity (H3-K4 specific). It is involved in the biological process described with: histone H3-K4 trimethylation. | 0.965 |
Cpsf100 | Cpsf160 | FBpp0084726 | FBpp0089163 | Probable cleavage and polyadenylation specificity factor subunit 2; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Required for the cotranscriptional processing of 3'- ends of polyadenylated and histone pre-mRNA. | Cleavage and polyadenylation specificity factor subunit 1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity); Belongs to the CPSF1 family. | 0.999 |
Cpsf100 | Cpsf73 | FBpp0084726 | FBpp0083105 | Probable cleavage and polyadenylation specificity factor subunit 2; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Required for the cotranscriptional processing of 3'- ends of polyadenylated and histone pre-mRNA. | Cleavage and polyadenylation specificity factor 73; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Has endonuclease activity and functions as mRNA 3'- end-processing endonuclease. Required for the cotranscriptional processing of 3'-ends of polyadenylated and histone pre-mRNA. Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lacta [...] | 0.999 |
Cpsf100 | Pp1alpha-96A | FBpp0084726 | FBpp0306442 | Probable cleavage and polyadenylation specificity factor subunit 2; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Required for the cotranscriptional processing of 3'- ends of polyadenylated and histone pre-mRNA. | Serine/threonine-protein phosphatase alpha-1 isoform; Protein phosphatase 1alpha at 96A (Pp1alpha-96A) encodes a phosphatase involved in the regulation of Hedgehog and Wnt signaling pathways. | 0.824 |
Cpsf100 | Ssu72 | FBpp0084726 | FBpp0074516 | Probable cleavage and polyadenylation specificity factor subunit 2; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Required for the cotranscriptional processing of 3'- ends of polyadenylated and histone pre-mRNA. | Ssu72 CTD phosphatase (Ssu72) encodes an RNA polymerase II C-terminal domain (CTD) phosphatase. Its phosphatase activity is important for RNAPII transcription and termination and for gene looping. It may also be involved in the regulation of sister chromatid cohesion. | 0.996 |
Cpsf100 | Wdr33 | FBpp0084726 | FBpp0078362 | Probable cleavage and polyadenylation specificity factor subunit 2; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Required for the cotranscriptional processing of 3'- ends of polyadenylated and histone pre-mRNA. | WD repeat domain 33, isoform A; It is involved in the biological process described with: mRNA polyadenylation. | 0.999 |
Cpsf100 | Wdr82 | FBpp0084726 | FBpp0079266 | Probable cleavage and polyadenylation specificity factor subunit 2; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Required for the cotranscriptional processing of 3'- ends of polyadenylated and histone pre-mRNA. | WD repeat domain 82 (Wdr82) encodes a component of the Compass complex, which performs K4 methylation of the histone encoded by His3. | 0.966 |
Cpsf160 | CG3515 | FBpp0089163 | FBpp0077430 | Cleavage and polyadenylation specificity factor subunit 1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity); Belongs to the CPSF1 family. | FI19335p1; Chromatin binding; histone methyltransferase activity (H3-K4 specific). It is involved in the biological process described with: histone H3-K4 trimethylation. | 0.965 |
Cpsf160 | Cpsf100 | FBpp0089163 | FBpp0084726 | Cleavage and polyadenylation specificity factor subunit 1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity); Belongs to the CPSF1 family. | Probable cleavage and polyadenylation specificity factor subunit 2; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Required for the cotranscriptional processing of 3'- ends of polyadenylated and histone pre-mRNA. | 0.999 |
Cpsf160 | Cpsf73 | FBpp0089163 | FBpp0083105 | Cleavage and polyadenylation specificity factor subunit 1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity); Belongs to the CPSF1 family. | Cleavage and polyadenylation specificity factor 73; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Has endonuclease activity and functions as mRNA 3'- end-processing endonuclease. Required for the cotranscriptional processing of 3'-ends of polyadenylated and histone pre-mRNA. Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lacta [...] | 0.999 |
Cpsf160 | Pp1alpha-96A | FBpp0089163 | FBpp0306442 | Cleavage and polyadenylation specificity factor subunit 1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity); Belongs to the CPSF1 family. | Serine/threonine-protein phosphatase alpha-1 isoform; Protein phosphatase 1alpha at 96A (Pp1alpha-96A) encodes a phosphatase involved in the regulation of Hedgehog and Wnt signaling pathways. | 0.830 |
Cpsf160 | Ssu72 | FBpp0089163 | FBpp0074516 | Cleavage and polyadenylation specificity factor subunit 1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity); Belongs to the CPSF1 family. | Ssu72 CTD phosphatase (Ssu72) encodes an RNA polymerase II C-terminal domain (CTD) phosphatase. Its phosphatase activity is important for RNAPII transcription and termination and for gene looping. It may also be involved in the regulation of sister chromatid cohesion. | 0.996 |
Cpsf160 | Wdr33 | FBpp0089163 | FBpp0078362 | Cleavage and polyadenylation specificity factor subunit 1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity); Belongs to the CPSF1 family. | WD repeat domain 33, isoform A; It is involved in the biological process described with: mRNA polyadenylation. | 0.999 |