STRINGSTRING
Osbp protein (fruit fly) - STRING interaction network
"Osbp" - Oxysterol binding protein is important for sperm development in Drosophila melanogaster
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OsbpOxysterol binding protein is important for sperm development; Belongs to the OSBP family (784 aa)    
Predicted Functional Partners:
Vap-33A
VAMP-associated protein 33kDa, isoform B; VAMP-associated protein 33kD (Vap33) plays a conserved role in synaptic homeostasis. Vap33 controls a number of processes which depend on phosphoinositide levels, such as synaptic growth and axonal transport. Vap33 binds to Sac1 to maintain normal levels of phosphoinositides and to Dscam1 to affect its localization within axonal projections (269 aa)
       
  0.999
fan
Farinelli is an important protein for sperm development that interacts with Osbp (218 aa)
       
  0.992
cert
Ceramide transfer protein, isoform A; Phosphatidylinositol-4-phosphate binding; protein serine/threonine kinase activity; ceramide transporter activity; ceramide binding. It is involved in the biological process described with- sphingolipid metabolic process; ER to Golgi ceramide transport; ceramide transport (601 aa)
     
 
0.939
Sac1
Phosphatidylinositide phosphatase SAC1; Phosphoinositide phosphatase that hydrolyzes PtdIns(3)P and PtdIns(4)P. Has low activity towards PtdIns(3,5)P2 (By similarity) (592 aa)
     
 
  0.918
CG7115
CG7115, isoform A; Protein serine/threonine phosphatase activity. It is involved in the biological process described with- protein dephosphorylation; regulation of cell shape; cell adhesion (524 aa)
     
 
  0.901
Vap-33B
Uncharacterized protein, isoform D; Structural molecule activity. It is involved in the biological process described with- neurogenesis (498 aa)
       
 
  0.884
zw2
Phosphatidylinositol 4-kinase III alpha (PI4KIIIalpha) is a lipid kinase that synthesizes phosphatidylinositol 4-phosphate from phosphatidylinositol. PI4KIIIalpha roles include localization of plasma membrane-associated cytoskeletal and membrane trafficking proteins, Hippo signaling regulation and polarization of developing oocytes; Belongs to the PI3/PI4-kinase family (2154 aa)
     
 
  0.865
PKD
Protein Kinase D is a Ser/Thr kinase of the PKC family of Ca[2+]/calmodulin-dependent protein kinases. It regulates actin-dynamics by controlling ssh phosphatase activity (836 aa)
           
  0.787
Npc2a
Protein NPC2 homolog; Functions redundantly with Npc2b in regulating sterol homeostasis and ecdysteroid biosynthesis, probably by controlling the availability of sterol substrate (148 aa)
           
  0.693
Arf79F
ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells (182 aa)
     
 
  0.669
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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